Results 41 to 50 of about 1,135,884 (299)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Examining the Challenges of Scientific Workflows

, 2007
Workflows have recently emerged as a paradigm for representing and managing complex distributed scientific computations and therefore accelerate the pace of scientific progress.
Gannon, Dennis, Fox, Geoffrey, Myers, Jim, Ellisman, Mark, Gil, Yolanda, Deelman, Ewa, Fahringer, Thomas, Goble, Carole, Livny, Miron, Moreau, Luc   +9 more
core   +1 more source

Progress in the field of iodine deficiency disorders prevention in Republic of Uzbekistan (1998–2016)

Клиническая и экспериментальная тиреоидология, 2017
In spite of the works performed against IDD, it still remains severe in Uzbekistan. Progress to lower iodine deficiency was due to the activities to liquidation of iodine deficiency disorders (IDD) including supply with iodizing equipment and ...
Said I. Ismailov, Murodjon M. Rashitov
doaj   +1 more source

Three-dimensional assessment of the relative position of the roots of the teeth in the anterior lower jaw for treatment planning for class III occlusion anomalies using mini-implants

Эндодонтия Today, 2020
Relevance. The use of skeletal support in orthodontics led to the use of elastic traction and mini-implants for upper jaw traction in class III treatment, however, when planning the placement, clinicians did not take into account the anatomical ...
V. A. Mazhnikova, A. A. Abramyan, M. M. Shubitidze, Sh. M. Solimanov, A. O. Kuznetsova, R. V. Volberg   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Telemedicine consultation «patient-doctor» in child psychiatry: methodology and practice

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2022
Telepsychiatric assistance in the “doctor-patient” format is at the stage of formation and requires the solution of legal, organizational and methodological issues. The aim of the study was to substantiate the methodology of telemedicine consultations of
S P Morozov, M A Bebchuk, A V Vladzymyrskyy, O Z Khairetdinov   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Use of a quantitative data report in a hypothetical decision scenario for health policymaking: a computer-assisted laboratory study

BMC Medical Informatics and Decision Making, 2021
Background Quantitative data reports are widely produced to inform health policy decisions. Policymakers are expected to critically assess provided information in order to incorporate the best available evidence into the decision-making process.
Pamela Wronski, Michel Wensing, Sucheta Ghosh, Lukas Gärttner, Wolfgang Müller, Jan Koetsenruijter   +5 more
doaj   +1 more source

Vasilyuk's Scientific Heritage: Theory, Practice, Education

Консультативная психология и психотерапия, 2023
The paper presents the review of scientific meetings dedicated to the 70th anniversary of the birth of Doctor of Psychology, Professor Fyodor Efimovich Vasilyuk (October 6, 2023, Moscow). The purpose of the event: discussion of F.E. Vasilyuk's
T.D. Karyagina, E.V. Sheryagina, E.S. Mazaeva   +2 more
doaj   +1 more source

Scientific Justification of Cryonics Practice [PDF]

Rejuvenation Research, 2008
Very low temperatures create conditions that can preserve tissue for centuries, possibly including the neurological basis of the human mind. Through a process called vitrification, brain tissue can be cooled to cryogenic temperatures without ice formation.
openaire   +2 more sources