Results 61 to 70 of about 1,135,884 (299)
Use of office spirometers in Flemish general practice: results of a telephone survey
Monaldi Archives for Chest Disease, 2016 Background. While office spirometry is seen as potentially useful and feasible in general practice, little is known about its use in Flemish general practice.
N. Boffin +3 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Scientific management practice in Britain : a history [PDF]
This study traces the influence of scientific management on the development of modem management methods in Britain from the end of the 19th century to the outbreak of the second world war.
Whitston, Kevin
core
The Role of Justification in the Ordinary Concept of Scientific Progress [PDF]
, 2013 Alexander Bird and Darrell Rowbottom have argued for two competing accounts of the concept of scientific progress. For Bird, progress consists in the accumulation of scientific knowledge.
Mizrahi, Moti, Buckwalter, Wesley
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Scientific models: meaning and role in scientific practice
Revista Científica, 2017 This article aims to contribute to a better understanding of the scientific models as a key component of the nature of science. For this, firstly the epistemological meaning of the scientific models and their role in the scientific practice are discussed.
José Antonio Acevedo-Díaz +3 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
PSYCHO-EMOTIONAL CHANGES IN PATIENTS WITH CHRONIC HEART FAILURE
Евразийский Кардиологический Журнал, 2016 Objectives. To define the presence and severity of anxiety and depression stress and assess the impact produced on the life quality in subjects with CHF secondary to registered macrofocal (Q wave) myocardial infarction in medical history.
S. A. Matskevich +3 more
doaj +1 more source