Results 121 to 130 of about 12,733,834 (284)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Methodological approaches to the assessment of pharmaceutical substances neurotoxicity
Регуляторные исследования и экспертиза лекарственных средств, 2018 The article reviews methodological approaches to the assessment of pharmaceutical substances neurotoxicity. It describes the main battery of animal tests that are conducted prior to clinical trials in order to assess drug effects on the functioning of ...
M. N. Makarova +2 more
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
MAN-MADE RADIONUCLIDES IN THE NEAR-THE-GROUND ATMOSPHERIC LAYER DUE TO THE FUKUSHIMA ACCIDENT
Радиационная гигиена, 2015 The article presents information about the main observation results of radiometric departments of the Federal Service for Hydrometeorology and Environmental Monitoring for changes in the radiation situation on the territory of Russia following the ...
V. G. Bulgakov +5 more
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Reproductive MedicineBackground/Objectives: Non-receptive endometrium is associated with recurrent implantation failure, which leads to a decrease in the frequency of pregnancy during IVF; therefore, new treatment methods such as the use of Platelet-Rich Plasma (PRP) are ...
Ramilya K. Potapova +6 more
doaj +1 more source
Steps to successful rice production [PDF]
, 2015 Useful guides, from seed to market, to attain success in rice ...
Rice Production Manual +1 more
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
The Origins of Industrial Scientific Discoveries [PDF]
This paper estimates science production functions for R&D-performing firms in the United States using scientific papers as the measure of output, by analogy with patents. The underlying evidence covers 200 top U.S.
J. Roger Clemmons, James D. Adams
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