Results 61 to 70 of about 1,611,826 (291)

Scientific production of Bolivian universities

open access: yes, 2022
Introduction: higher education is undergoing significant changes due to the existence of agents promoting substantial changes in universities.Objective: to evaluate the scientific production of Bolivian universities in the Scopus database through a ...
Auza-Santiváñez, Jhossmar Cristians   +5 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Comparative research of bounding box based and image segmentation based neural network models for individual cattle identification [PDF]

open access: yesE3S Web of Conferences
Software and hardware based tools for collecting information about animals are an important part of most large agricultural enterprises. Various information collection methods and technologies help farmers to receive data about the health, behavior and ...
Shilin Denis   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Scientific Method

open access: yes, 2008
Many think the scientific method is a complicated formula used only by those with a degree in chemistry. In reality, the scientific method is a system of reasoning which can be used to solve almost any type of problem.

core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The high-voltage lateral p-channel MOS-transistor making optimization

open access: yesТехнологія та конструювання в електронній апаратурі, 2006
Simulation of semiconductor structures provides an opportunity to reduce manufacturing costs and optimize the parameters of integrated circuit elements and devices.
N. I. Leonov   +3 more
doaj  

Sharp interfaces in p+-AlGaAs/n-GaAs epitaxial structures obtained by MOCVD

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2014
The complexity of forming sharp and high-quality boundaries in p+AlGaAs/n-GaAs systems by MOCVD method is caused by differing on 80–120°С optimal crystallization temperature of GaAs layers and n-AlGaAs solid solutions.
N. M. Vakiv   +4 more
doaj   +1 more source

scientific production by country

open access: yes, 2016
scientific production about concept maps by ...
Roberto Baelo (1390567)
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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