Results 71 to 80 of about 12,733,834 (284)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The high-voltage lateral p-channel MOS-transistor making optimization

Технологія та конструювання в електронній апаратурі, 2006
Simulation of semiconductor structures provides an opportunity to reduce manufacturing costs and optimize the parameters of integrated circuit elements and devices.
N. I. Leonov, A. M. Lemeshevskaya, N. L. Dudar, S. N. Getzman   +3 more
doaj  

Cuban scientific production on diabetes, 2000–2017: Peer-reviewed Publications, Collaboration and Impact

, 2019
INTRODUCTION The steadily increasing prevalence of diabetes globally has captured researchers’ attention. Cuban production of scientific articles on diabetes has not been studied from a bibliometric perspective. OBJECTIVE Characterize the production and
Dorta-Contreras, A.J., Arencibia-Jorge, R., Fornaris-Cedeño, Y., Pacheco-Mendoza, J., Corrales-Reyes, I.E., Mejia, C.R.   +5 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Scientific management practice in Britain : a history [PDF]

This study traces the influence of scientific management on the development of modem management methods in Britain from the end of the 19th century to the outbreak of the second world war.
Whitston, Kevin
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

PROTOCOL OF REGISTRATION OF MAINTENANCE OF PIPELINE FITTINGS

Надежность и качество сложных систем
Background. The method of registration of maintenance and repair of pipeline fittings using RFID technology (Radio Frequency Identification, radio frequency identification) is considered.
D.S. Boyarkin, E.A. Aseev, D.A. Golushko, I.R. Abuzyarov, A.V. Lysenko   +4 more
doaj   +1 more source

Reliability and Quality of Complex Systems

Надежность и качество сложных систем
Background. Prolonged operation of shut-off valves of main gas pipelines leads to gradual wear of the sealing elements of ball valves and valves and a violation of their tightness.
D.S. Boyarkin, V.D. Yezhizhanskiy, D.A. Golushko, A.Yu. Kirsanov, A.V. Lysenko   +4 more
doaj   +2 more sources

Comparative research of bounding box based and image segmentation based neural network models for individual cattle identification [PDF]

E3S Web of Conferences
Software and hardware based tools for collecting information about animals are an important part of most large agricultural enterprises. Various information collection methods and technologies help farmers to receive data about the health, behavior and ...
Shilin Denis, Shubin Ivan, Shestov Dmitry   +2 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source