Results 61 to 70 of about 5,766,021 (361)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Analyzing Citation-Distance Networks for Evaluating Publication Impact [PDF]

, 2018
Studying citation patterns of scholarly articles has been of interest to many researchers from various disciplines. While the relationship of citations and scientific impact has been widely studied in the literature, in this paper we develop the idea of ...
Herrmannova, Drahomira, Knoth, Petr, Patton, Robert   +2 more
core  

Influenza : a scientometric and density-equalizing analysis [PDF]

, 2013
Background: Novel influenza in 2009 caused by H1N1, as well as the seasonal influenza, still are a challenge for the public health sectors worldwide.
Fricke, Ralph, Groneberg, Jan David Alexander, Klingelhöfer, Doris, Uibel, Stefanie   +3 more
core   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

SemEval 2017 Task 10: ScienceIE - Extracting Keyphrases and Relations from Scientific Publications [PDF]

International Workshop on Semantic Evaluation, 2017
We describe the SemEval task of extracting keyphrases and relations between them from scientific documents, which is crucial for understanding which publications describe which processes, tasks and materials.
Isabelle Augenstein, Mrinal Das, Sebastian Riedel, Lakshmi Vikraman, A. McCallum   +4 more
semanticscholar   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Research Collaboration Analysis Using Text and Graph Features [PDF]

, 2018
Patterns of scientific collaboration and their effect on scientific production have been the subject of many studies. In this paper we analyze the nature of ties between co-authors and study collaboration patterns in science from the perspective of ...
Herrmannova, Drahomira, Knoth, Petr, Patton, Robert, Stahl, Christopher, Wells, Jack   +4 more
core  

Current trends in scientific journals, the way forward

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2018
Full text (Español)
Elso Manuel Cruz-Cruz
doaj  

Performance and Factors Inhibiting Research and Scientific Publication of Universitas Terbuka Indonesia Lecturers

Publik, 2021
Efforts to improve the performance of research and scientific publications in Indonesian universities are still a challenge. Various problems often become an inhibiting factor for lecturers' research performance.
Tri Yulianto, Vishnu Juwono
doaj   +1 more source