Results 81 to 90 of about 1,279,520 (308)

Research trends in nanotechnology studies across geo-economic areas [PDF]

The purpose of this paper is to analyze the current temporal and spatial research trajectories in nanoscience and nanotechnology studies in order to display the worldwide patterns of research fields across main economic players.
Diego Margon, Mario Coccia, Ugo Finardi
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Patenting Behavior of Academic Founders [PDF]

, 2010
This study explores why academic entrepreneurs patent their inventions before and after creating a firm. Drawing on start-up data combined with patent data, we specifically examine the impact of five, relatively under-researched factors (scientific field,
Schmidt, Arne, Walter, Achim, Walter, Sascha G.   +2 more
core  

Technological safety of sustainable development of coal enterprises [PDF]

, 2017
Purpose. Substantiation of conceptual base of searching the ways of threats prevention to sustainable development of coal enterprises in the presence of multidirectional vectors of economic pressure of the external environment. Methods.
Bondarenko, V, Cawood, F, Cherniak, V, Chervatiuk, V   +3 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A FRAMEWORK FOR THE ECONOMIC EVALUATION OF ENVIRONMENTAL SCIENCE [PDF]

Economists, especially agricultural economists, have undertaken extensive analysis of the gains of technological-based scientific research. This is in stark contrast to the efforts undertaken to understand the economic effects of environmental scientific
Kutschukian, Jean-Marc
core   +1 more source

Simulation of deposit parameters in underground development mining [PDF]

, 2018
The article is aimed at improving development mining to prepare an ore body for stoping by access ramps to provide comfortable conditions and high technical and economic indices in underground mining.
Golik, Vladimir, Morkun, Nataliia, Morkun, Volodymyr, Razorenov, Yuriy   +3 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Eggshell waste bioprocessing for sustainable acid phosphatase production and minimizing environmental hazards

Journal of Biological Engineering
Background The Environmental Protection Agency has listed eggshell waste as the 15th most significant food industry pollution hazard. Using eggshell waste as a renewable energy source has been a hot topic recently.
Soad Abubakr Abdelgalil, Mohamed Mohamed Yousri Kaddah, Gaber Attia Abo-Zaid   +2 more
doaj   +1 more source

Evaluating the safety and efficacy of Lacticaseibacillus paracasei TISTR 2593 as a therapeutic probiotic for obesity prevention

Frontiers in Microbiology
Several recent studies have reported the potential of probiotics in reducing body weight and fat mass and improving glucose and lipid metabolism. Therefore, probiotic administration is considered an alternative approach for treating obesity.
Jaruwan Sitdhipol, Kanidta Niwasabutra, Neungnut Chaiyawan, Kamonsri Nuankham, Thanaphol Thanagornyothin, Somboon Tanasupawat, Wasaporn Preteseille Chanput, Pongsathon Phapugrangkul, Chaivarakun Chaipanya, Sukanya Phuengjayaem, Saranporn Poothong, Engkarat Kingkaew   +11 more
doaj   +1 more source