Results 71 to 80 of about 1,279,520 (308)

The model of specialists training system for high-tech industries [PDF]

, 2017
The article reviews the world experience of the specialist training model for high-tech industries. The focus is made on the approach to organization of training to help students develop enterprise-technological skills implemented in National Research ...
Mertins, Kseniya Viktorovna, Shagdyrov, Anton, Soloviev, Mikhail Aleksandrovich   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Software Platforms for Smart Cities: Concepts, Requirements, Challenges, and a Unified Reference Architecture

, 2017
Making cities smarter help improve city services and increase citizens' quality of life. Information and communication technologies (ICT) are fundamental for progressing towards smarter city environments. Smart City software platforms potentially support
Chaves, Ana Paula, Gerosa, Marco Aurelio, Kon, Fabio, Milojicic, Dejan, Santana, Eduardo Felipe Zambom   +4 more
core   +1 more source

POTENTIAL PROBLEMS OF GLOBAL SCIENTIFIC RESEARCH, TECHNOLOGICAL DEVELOPMENT AND INNOVATION [PDF]

USV Annals of Economics and Public Administration, 2015
In the commercial companies and autonomous administrations there are strong R&D units subordinated thereto, involved in the research activity, especially by free market competition, and not in the last place we need to highlight this creative technical activity with individual title by natural persons.
Gabriel I. NÃSTASE, Luana Florentina PASCU, Bogdan PASCU   +2 more
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Technological agglomeration and the emergence of clusters and networks in nanotechnology [PDF]

Research and development at the nanoscale requires a large degree of integration, from convergence of research disciplines in new fields of enquiry to new linkages between start-ups, regional actors and research facilities.
Arie Rip, Douglas Robinson, Vincent Mangematin   +2 more
core  

Technological stages in the development of scientific writing and their impact on the research process

Humanitarian Military Journal
Technology advances have revolutionized the process of producing scientific texts, from the era of manuscripts to contemporary artificial intelligence solutions. The authors conducted a historical and methodological analysis of the development of scientific writing and communications, highlighting key stages, including the printing press, typewriters ...
Shaikat Z. Khubbiev, Mikhail S. Obraztsov, Vitalii B. Kessel   +2 more
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Induction of Plant Resistance against Tobacco Mosaic Virus Using the Biocontrol Agent Streptomyces cellulosae Isolate Actino 48

Agronomy, 2020
Viral plant diseases represent a serious problem in agricultural production, causing large shortages in the production of food crops. Eco-friendly approaches are used in controlling viral plant infections, such as biocontrol agents. In the current study,
Gaber Attia Abo-Zaid, Saleh Mohamed Matar, Ahmed Abdelkhalek   +2 more
doaj   +1 more source