Results 31 to 40 of about 4,153,632 (305)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Reflections on historiography in connection with Vladimir Fyodorovich Gening’s anniversary

open access: yesПоволжская археология, 2014
In connection with the 90 years’ anniversary of Vladimir Fyodorovich Gening (1924 – 1993), an eminent Soviet archaeologist, the milestones of the scholar’s biography and the principal directions of his research activity are traced in the article. A brief
Melnikova Olga M.
doaj   +1 more source

EPOXI Mission: Comet on a Stick [PDF]

open access: yes, 2009
In this activity, students examine their concepts of a comet by designing and building a model. The goal is to have students replicate the scientific processes of observing, modeling, forming an explanation, making new observations, and revising. In this
John Risvey
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

History and modernity of the economy of railway transport in the works of VNIIZHT scientists

open access: yesВестник Научно-исследовательского института железнодорожного транспорта, 2021
The article reflects the most important areas of work and the contribution of scientists of the Department of Economics and Finance of the JSC “VNIIZHT” (now the scientific center “Economics of Complex Projects and Tariff Formation”) in the development ...
L. A. Mazo   +2 more
doaj   +1 more source

Space Math: Hinode Math [PDF]

open access: yes, 2008
This booklet is a collection of 15 problems that incorporate data from the Hinode solar observatory. These problems cover topics in sunspot structure, spectroscopy, solar rotation, magnetic fields, density and temperature of hot gases, and solar flares ...
Sten Odenwald
core  

Greenhouse Effect in the Classroom: A Project- and Laboratory-Based Curriculum [PDF]

open access: yes, 2001
This article describes a multifaceted curriculum for use in earth science classes from secondary school to undergraduate level. The centerpiece of the curriculum is a project-based investigation of greenhouse warming that can be conducted during one or ...
Nicholas Pinter
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Kazan scientific school of journalism: Definition of paradigmatic boundaries

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2017
The paper summarizes the preliminary results, outlines the milestones and the prospects for the formation and development of the Kazan school of journalism.
D.V. Tumanov   +2 more
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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