Results 51 to 60 of about 4,143,379 (303)
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2021 Basic stages of creation, development and spreading of academician L. A. Orbeli scientific school at Petrograd - Leningrad were traced. Significance of main scientific researches of this school in the physiology for the development of adjacent areas of ...
V. V. Kolbanov
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FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Philosophical school of D. V. Pivovarov: current state and development potential
Интеллект. Инновации. ИнвестицииThe relevance of the problem being developed is due to the fact that, on the one hand, quite significant attention is paid to the study of philosophical schools in modern literature.
I. A. Belyaev, A. M. Maksimov
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FAMILY DYNASTIES IN THE HISTORY OF RUSSIAN SCIENCE
Гуманитарные и юридические исследования, 2021 The article deals with scientific dynasties which existed in our country and contributed to the development of its scientific and intellectual potential.
G. Andreychenko, E. Saprykina
doaj
Teacher training processes and teachers' competence : A sociological study in the primary school [PDF]
, 2005 The paper describes part of a study whose aim was to investigate the relation between modalities of teacher training and modalities of pedagogic practice implemented in the science classroom.
Afonso, Margarida +2 more
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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Supernova Educator's Guide [PDF]
, 2008 This educator’s guide features three curriculum enhancement activities and one scientific literacy activity, extensive background information, assessment rubrics, student worksheets, extension and transfer activities, and detailed information about the ...
core
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
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