Results 61 to 70 of about 1,651,911 (310)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Scientific schools of the Federal Scientific Vegetable Center: continuity and modernity
Овощи РоссииRelevance. The article analyzes the historical prerequisites and conditions that ensured the active formation and progressive development of the Federal State Budgetary Scientific Institution of the Russian Academy of Natural Sciences as the country's ...
A. V. Soldatenko +3 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
School of English for Political Scientist
Vestnik MGIMO-Universiteta, 2014 Department of English Language № 7 was founded in 2001. Originally its teaching staff included the specialists of the Department of English Language Chair.
Irina A. Mazaeva
doaj
Listening to Young People’s Perspectives on Out-of-School Time Opportunities [PDF]
, 2004 This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu.Youth Voices focus groups were conducted with 101 middle ...
Saito, Rebecca +1 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Учёт. Анализ. АудитHaving your own scientific school is an important component of the activities of any scientific team: it forms traditions, fundamental principles and base, and a commonality of views of researchers, acting as the basis for the development of both the ...
O. A. Naumova +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
NEW RESEARCH PARADIGMS AND ESTABLISHMENT OF THE UNIVERSITY SCIENTIFIC SCHOOL
Вестник Кемеровского государственного университета, 2013 The paper focuses on the scientific school “Russian literature in the context of Christian culture” at Kemerovo State University, which was established since a new sphere of the literary study in Russia was being developped.
O. V. Pichugina, L. A. Hodanen
doaj