Results 61 to 70 of about 1,479,471 (264)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Having your own scientific school is an important component of the activities of any scientific team: it forms traditions, fundamental principles and base, and a commonality of views of researchers, acting as the basis for the development of both the ...
O. A. Naumova +2 more
doaj +1 more source
Methodology of Modern Rhetorical Education: Russian Scientific Schools
The article is devoted to the description of the activities of Russian scientific schools in theoretical and pedagogical understanding of rhetoric as a science of the laws and rules of effective and appropriate speech.
V. I. Annushkin, A. V. Shcherbakov
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
NEW RESEARCH PARADIGMS AND ESTABLISHMENT OF THE UNIVERSITY SCIENTIFIC SCHOOL
The paper focuses on the scientific school “Russian literature in the context of Christian culture” at Kemerovo State University, which was established since a new sphere of the literary study in Russia was being developped.
O. V. Pichugina, L. A. Hodanen
doaj
Systems approach in construction—scientific school of a. A. Gusakov (social-communicative survey)
The scientific school of Academician A. A. Gusakov “Systems engineering in construction†has been approached by a social-communicative model. Scientists belonging to the above school have been identified and the period of the school formation has ...
Edmundas Zavadskas +1 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source

