Results 61 to 70 of about 4,153,632 (305)

Law-Based Arguments and Messages to Advocate for Later School Start Time Policies in the United States [PDF]

, 2017
The increasing scientific evidence that early school start times are harmful to the health and safety of teenagers has generated much recent debate about changing school start times policies for adolescent students.
Lee, Clark J, Lockley, Steven W, Nolan, Dennis M, Pattison, Brent   +3 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Scientific schools of the Federal Scientific Vegetable Center: continuity and modernity

Овощи России
Relevance. The article analyzes the historical prerequisites and conditions that ensured the active formation and progressive development of the Federal State Budgetary Scientific Institution of the Russian Academy of Natural Sciences as the country's ...
A. V. Soldatenko, O. N. Pyshnaya, L. K. Gurkina, E. V. Pinchuk   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

School of English for Political Scientist

Vestnik MGIMO-Universiteta, 2014
Department of English Language № 7 was founded in 2001. Originally its teaching staff included the specialists of the Department of English Language Chair.
Irina A. Mazaeva
doaj  

Developing Digital Competences. Work learn trajectories in Italian School System [PDF]

, 2017
The work based learning is the core European dispositions on educational and training issue and a pillar of the Europe 2020 strategy (EUCOM 2009/C119/02).
LO PRESTI, Veronica
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Development of the Scientific School of the Department of Accounting, Analysis and Economic Security of the Samara State University of Economics

Учёт. Анализ. Аудит
Having your own scientific school is an important component of the activities of any scientific team: it forms traditions, fundamental principles and base, and a commonality of views of researchers, acting as the basis for the development of both the ...
O. A. Naumova, T. M. Tarasova, Yu. A. Tatarovsky   +2 more
doaj   +1 more source

Children's acquisition of science terms: simple exposure is insufficient [PDF]

, 2007
The ability of school children (N = 233) to acquire new scientific vocabulary was examined. Children from two age groups (M = 4;8 and M = 6;5) were introduced to previously unknown words in an educational video.
Best, R, Braisby, N, Dockrell, Julie
core   +1 more source