Results 111 to 120 of about 1,730,357 (294)

A Metadata-Enabled Scientific Discourse Platform [PDF]

open access: yes, 2010
Scientific papers and scientific conferences are still, despite the emergence of several new dissemination technologies, the de-facto standard in which scientific knowledge is consumed and discussed.
Chenu-Abente, Ronald   +3 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The PoGOLite control system and software

open access: yes, 2013
The autonomous control system of PoGOLite is presented. PoGOLite is a balloon borne X-ray polarimeter designed to observe point sources. To obtain scientific data with optimal efficiency, independent of the ground connection, the payload control system ...
Jackson, M. S.
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Sciunits: Reusable Research Objects

open access: yes, 2017
Science is conducted collaboratively, often requiring knowledge sharing about computational experiments. When experiments include only datasets, they can be shared using Uniform Resource Identifiers (URIs) or Digital Object Identifiers (DOIs).
Fils, Gabriel   +3 more
core   +1 more source

Mikrozensus Scientific Use File 2003: Dokumentation und Datenaufbereitung

open access: yes, 2005
"In dem vorliegenden ZUMA-Methodenbericht werden nach einer kurzen Beschreibung des Erhebungsprogramms, der Stichprobe und der Besonderheiten des Mikrozensus 2003 die einzelnen Schritte der Aufbereitung der faktisch anonymisierten Mikrozensusdaten (des Scientific Use Files) dargestellt.
Shahla, Hossein   +2 more
openaire   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

INNBC DApp, a decentralized application to permanently store biomedical data on a modern, proof-of-stake (POS), blockchain such as BNB Smart Chain

open access: yesBMC Medical Informatics and Decision Making
Background A blockchain can be described as a distributed ledger database where, under a consensus mechanism, data are permanently stored in records, called blocks, linked together with cryptography.
Jonathan Fior
doaj   +1 more source

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