Results 91 to 100 of about 1,730,357 (294)

CaosDB - Research Data Management for Complex, Changing, and Automated Research Workflows

, 2018
Here we present CaosDB, a Research Data Management System (RDMS) designed to ensure seamless integration of inhomogeneous data sources and repositories of legacy data.
Fitschen, Timm, Hornung, Daniel, Luther, Stefan, Parlitz, Ulrich, Schlemmer, Alexander, Wörden, Henrik tom   +5 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Computing infrastructure issues in distributed communications systems : a survey of operating system transport system architectures [PDF]

, 1992
The performance of distributed applications (such as file transfer, remote login, tele-conferencing, full-motion video, and scientific visualization) is influenced by several factors that interact in complex ways.
Schmidt, Douglas C., Suda, Tatsuya
core  

Mikrozensus Scientific Use File 2007: Dokumentation und Datenaufbereitung

, 2010
"Die Aufbereitung und Dokumentation des faktisch anonymisierten Einzelmaterials des Mikrozensus als Scientific Use File erfolgt durch das Statistische Bundesamt, Gruppe VIII C - Mikrozensus, in Kooperation mit dem German Microdata Lab der GESIS. In dem vorliegenden Methodenbericht werden das Erhebungsprogramm und der Stichprobenplan des Mikrozensus im ...
Thirolf, Florian, Jäger, Delia, Langeheine, Malte, Lechert, Yvonne, Lohel, Freya, Siegel, Tony, Schimpl-Neimanns, Bernhard   +6 more
openaire   +1 more source

Additional file 1 of Investigating and preventing scientific misconduct using Benford’s Law

, 2023
Additional file 1.
Eckhartt, Gregory M., Ruxton, Graeme D.
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Methods for Specifying Scientific Data Standards and Modeling Relationships with Applications to Neuroscience

Frontiers in Neuroinformatics, 2016
Neuroscience continues to experience a tremendous growth in data; in terms of the volume and variety of data, the velocity at which data is acquired, and in turn the veracity of data.
Oliver Ruebel, Max Dougherty, Mr. Prabhat, Peter Denes, David Conant, Edward Chang, Kristofer Bouchard   +6 more
doaj   +1 more source

Mikrozensus Scientific Use File 1985: Dokumentation und Datenaufbereitung

, 2008
In diesem Beitrag werden nach einer kurzen Beschreibung des Erhebungsprogramms, der Stichprobe und der Besonderheiten des Mikrozensus 1985, die einzelnen Schritte der Aufbereitung der faktisch anonymisierten Mikrozensusdaten dargestellt. Die Bereitstellung der faktisch anonymisierten Daten als Rohdatenfile in ASCII-Format erfolgt durch das ...
Lechert, Yvonne, Lohel, Freya
openaire   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source