Results 111 to 120 of about 2,371,308 (308)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Web Content Mining for Information on Information Scientists [PDF]
, 2011 This paper presents a search system for information on scientists which was implemented prototypically for the area of information science, employing Web Content Mining techniques.
Risse, Sarah
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Reinventing Storytelling as a Management Training Tool for Scientists [PDF]
Journal of Interdisciplinary SciencesThis point of departure essay brings into discussion the connection between storytelling, science and management. While the Biological Sciences field provides by default the technical training needed to acquire specific skills, the experts mastering ...
Gertrude-Emilia Costin +1 more
doaj
Development of organic farming in distant rural Māori communities in New Zealand through successful participatory approaches [PDF]
, 2008 A research partnership was initiated between scientists of Crop and Food Research and rural Māori communities in the Tairawhiti region of New Zealand to help these communities with the transition from extensive agriculture to intensive organic ...
Kerckhoffs, Dr. L.H.J.
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Вестник Мининского университета, 2017 The present article analyzes the history of formation and development of psychological education in Gorky Statе Pedagogical University (GSPU). The key stages and directions of scientific and pedagogical activity of psychological department of GSPU are ...
N. V. Shutova, V. V. Kisova
doaj