Results 131 to 140 of about 495,623 (265)

Variability in first academic medicine job offers in pulmonary and critical care medicine. [PDF]

ATS Sch
Olson EM, Modes ME, Rowe TJ, Lyons PG, Ingraham NE, Nadig NR, Schroedl CJ, Gao CA.   +7 more
europepmc   +1 more source

The Scientist in Society [PDF]

Public Health Reports (1896-1970), 1966
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A new hormonal marker for tracking rhino pregnancy. [PDF]

Conserv Physiol
Terry CE.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Biocomputing: Beyond the Hype. [PDF]

J Med Internet Res
Spichak S.
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Knowing your worth: a review of initial pulmonary and critical care academic offers. [PDF]

ATS Sch
Hinkle L.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Stabilizing and strengthening the US physician-scientist faculty workforce in academic medicine: a proposed institutional framework. [PDF]

JCI Insight
Williams CS, Allen M, Cooper-Byas P, Hawley J, Muglia LJ, Abel ED, Bastarache JA, Calfee C, Carethers JM, Cornfield DN, Eickelberg O, Gallagher EJ, Greka A, Gruber PJ, Hollenberg AN, Kong HH, Kazmierczak B, Koretzky GA, Lachs M, Lenschow DJ, Pitt G, Rockey DC, Satlin LM, Sleckman BP, Stoltz DA, Vyas JM, Wang TJ, Rhee KY.   +27 more
europepmc   +1 more source