Results 141 to 150 of about 827,817 (314)

Blueprint for a national water plan : a way forward from the Wentworth Group of concerned scientists

open access: yes, 2003
Wentworth Group of Concerned Scientists ...
Thom, Bruce   +10 more
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A role for scientists

open access: yes, 2007
The relevance of science in solving environmental problems is discussed with an emphasis on biological invasions.
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Forensic scientists detect 27 new recreational drugs.

open access: yes, 2017
Forensic scientists detected 27 new recreational drugs in Ireland last year which are manufactured as cheaper alternatives to narcotics such as cocaine and cannabis.....
Gallagher, Conor
core  

View from the Past – the Way to the Future

open access: yesУправление, 2016
This article describes the main developments and results of the emergence, formation and development of the scientific school of management theory. The article estimated place, role, contribution of the scientific school of State University of Management
M. V. Melnik
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Creative Little Scientists: enabling creativity through science and mathematics in preschool and first years of primary education: guidelines and curricula for teacher training (D5.2)

open access: yes, 2013
One of the key objectives of the Creative Little Scientists project is to propose a set of curriculum design principles as guidelines for European initial teacher education (ITE) and continuous professional development (CPD) programmes that will foster ...
Costa, Manuel F. M.   +3 more
core  

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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