Results 231 to 240 of about 2,371,308 (308)

Mass spectral proteomics checklist. [PDF]

J Biol Chem
Haltiwanger RS, Colbran RJ, Dohlman H, Graves L, Wells L.   +4 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Shaping science: Scholarly motivation and research outcomes in NIH-HEAL funded studies. [PDF]

PLoS One
Kushmerick-McCune B, Sawyer-Morris G, Ulukaya M, Clark K, Walters ST, Taxman FS.   +5 more
europepmc   +1 more source

UNH Scientists Document, Quantify Deep-Space Radiation Hazards [PDF]

, 2013
Sims, David
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Shedding light on public perceptions of scientists who engage in wrongness admission amidst a failed replication. [PDF]

Public Underst Sci
Evans ND, Fetterman AK.
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

The Tenuous Future of Our Next Generation of Physician-Scientists. [PDF]

ATS Sch
Schwartz DA.
europepmc   +1 more source

Scientists Estimate Size of the US Carbon Sink [PDF]

, 2001
Keeler, Sharon
core   +2 more sources