Results 241 to 250 of about 2,396,287 (305)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

There is No Consensus on Biological Sex. [PDF]

open access: yesEcol Lett
Eppley MG, Lee A, Dellinger R, Swank A.
europepmc   +1 more source

How can academic researchers more effectively contribute to environmental toxicology and health efforts for regulatory decisions, policymakers, nonprofits, and communities? [PDF]

open access: yesJ Toxicol Environ Health B Crit Rev
Meyer JN   +16 more
europepmc   +1 more source

Training biologists in Unix command-line skills: From curriculum to interactive online tutorials. [PDF]

open access: yesPLoS Comput Biol
Khamvongsa-Charbonnier L   +8 more
europepmc   +1 more source

Imagining an ethics for synthetic biology. [PDF]

open access: yesFront Genet
Aravind Paleri V, Hens K.
europepmc   +1 more source

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