Results 41 to 50 of about 529,003 (289)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

NaI(Tl) Detector Efficiency Computation Using Radioactive Parallelepiped Sources Based on Efficiency Transfer Principle

Science and Technology of Nuclear Installations, 2015
The efficiency transfer (ET) principle is considered as a simple numerical simulation method, which can be used to calculate the full-energy peak efficiency (FEPE) of 3″×3″ NaI(Tl) scintillation detector over a wide energy range.
Mohamed S. Badawi, Mona M. Gouda, Ahmed M. El-Khatib, Abouzeid A. Thabet, Ahmed A. Salim, Mahmoud I. Abbas   +5 more
doaj   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Inorganic scintillating materials and scintillation detectors

Proceedings of the Japan Academy, Series B, 2018
Scintillation materials and detectors that are used in many applications, such as medical imaging, security, oil-logging, high energy physics and non-destructive inspection, are reviewed. The fundamental physics understood today is explained, and common scintillators and scintillation detectors are introduced.
openaire   +3 more sources

Strong Coupling in Bulk Nanoplasmonic Nanoplatelet Perovskite Scintillators

Advanced Materials, EarlyView.
A bulk scintillating nanocomposite is engineered from CsPbBr3 nanoplatelets and Ag nanocubes to support exciton–plasmon strong coupling under X‐ray excitation. The resulting hybrid polaritonic states appear directly in radioluminescence, opening a route toward polariton‐enabled scintillator design beyond conventional Purcell enhancement.
Michal Makowski, Dominik Kowal, Anna Pniakowska, Kamil Misztal, Mohanad Saadeldin Eid, Joanna Cybinska, Winicjusz Drozdowski, Benoit Mahler, Christophe Dujardin, Detlef Hommel, Liang Jie Wong, Dennis Schaart, Sergio Brovelli, Muhammad Danang Birowosuto   +13 more
wiley   +1 more source

Conformal Coating and Transfer of 2D Nanomaterials via Dynamic Interface Engineering

Advanced Materials Interfaces, EarlyView.
This review discusses conformal coating and transfer of two‐dimensional (2D) nanomaterials with a focus on dynamic interface engineering. By actively regulating nanosheet transport and interfacial contact during film formation, recent dynamic coating strategies overcome the limitations of conventional passive approaches and enable geometry‐adaptive ...
Seungyeon Kim, Euihoon Jeong, Seoung‐Ki Lee, Sukang Bae, Tae‐Wook Kim   +4 more
wiley   +1 more source

The plastic scintillator detector for DAMPE [PDF]

Astroparticle Physics, 2017
he DArk Matter Particle Explorer (DAMPE) is a general purposed satellite-borne high energy $γ-$ray and cosmic ray detector, and among the scientific objectives of DAMPE are the searches for the origin of cosmic rays and an understanding of Dark Matter particles.
Yu, Yuhong, Sun, Zhiyu, Su, Hong, Yang, Yaqing, Liu, Jie, Kong, Jie, Xiao, Guoqing, Ma, Xinwen, Zhou, Yong, Zhao, Hongyun, Mo, Dan, Zhang, Yongjie, Yang, Peng, Chen, Junling, Yang, Haibo, Fang, Fang, Zhang, Shengxia, Yao, HuiJun, Duan, Jinglai, Niu, Xiaoyang, Hu, Zhengguo, Wang, Zhaomin, Wang, Xiaohui, Zhang, Jingzhe, Liu, Wenqiang   +24 more
openaire   +2 more sources

SCINTILLATION DETECTOR [PDF]

, 1999
FIELD: radiation detection. SUBSTANCE: proposed scintillation detector of gamma-radiation is meant for photodiode registration. Salient feature of invention lies in usage of spectrum mixer in the form of thin scintillation film or thin scintillation ...
Шульгин, Б. В., Rajkov, D. V., Shulgin, D. B., Sitnikov, E. G., Петров, В. Л., Шульгин, Д. Б., Коссе, А. И., Shulgin, B. V., Ситников, Е. Г., Kosse, A. I., Райков, Д. В., Petrov, V. L.   +11 more
core  

Advances in Halide Perovskites for Photon Radiation Detectors

Advanced Materials Technologies, EarlyView.
This work highlights recent progress in perovskite‐based photon radiation detectors, covering organic–inorganic hybrid, inorganic, lead‐free double, and vacancy‐ordered halide perovskites. Their detection performance is compared, material‐specific advantages and challenges are examined, and provides insight into current limitations and future ...
Liangling Wang, Jieqi Wang, Xiaojun Cui, Carsten Ronning   +3 more
wiley   +1 more source

Investigating the potential of conical scintillation detectors for patient-specific verification of intensity-modulated radiotherapy plans

Physics and Imaging in Radiation Oncology, 2020
Background and purpose: Conical scintillation detectors are frequently used to measure geometric characteristics of radiotherapy modalities. However, their application to verify intensity-modulated radiotherapy plan delivery has not been investigated and
Adam D. Yock, Levi S. Johnson, Michael Price   +2 more
doaj   +1 more source