Results 41 to 50 of about 48,334 (227)
Aim or Purpose: To describe the effect of varying scleral stiffness on the biomechanical deformation response of the cornea under air-puff loading via a finite-element (FE) model.Methods: A two-dimensional axisymmetric stationary FE model of the whole ...
B. Audrey Nguyen +4 more
doaj +1 more source
An electronics‐free smart scleral lens passively monitors dry eye disease‐related tear biomarkers through colorimetric sensing of chloride, pH, and ocular surface temperature. Smartphone‐assisted image analysis enables quantitative interpretation, providing a simple, non‐invasive strategy for ocular health monitoring without integrated electronics ...
Ziheng Wang +15 more
wiley +1 more source
Visual deprivation causes enhanced eye growth and the development of myopia, which is associated with a change in the arrangement of collagen fibers within the sclera.
Juan M. Bueno +3 more
doaj +1 more source
Response of the anterior sclera to accommodation in myopes and emmetropes [PDF]
• The biomechanical properties of the sclera are documented to be altered in eyes with myopia, with the myopic sclera thought to be more susceptible to deformation from otherwise normal ocular forces.\ud \ud • The close anatomical and functional ...
Read, Scott A. +3 more
core
PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski +6 more
wiley +1 more source
Understanding the spacing of placodes in the eye: A comparative study across age and species
Abstract The conjunctival placodes of the avian eye form in an intriguing and conserved sequence in a circular annulus around the cornea. These 13–16 placodes develop into papillae that are essential for inducing underlying intramembranous flat bones, known as scleral ossicles, which form an important part of the ocular skeleton.
Florence Joseph +1 more
wiley +1 more source
Porcine sclera dissected by scalpel blades.
Strips in the lower and upper sides of the figure are peripapillary sclera and sclera near the limbus, respectively. The four strips of sclera between them were used for the measurement.
Yiheng Lim (308441) +8 more
core +1 more source
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa +5 more
wiley +1 more source
Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf +5 more
wiley +1 more source
The Dynamic Scleral Extracellular Matrix Alterations in Chronic Ocular Hypertension Model of Rats
Intraocular pressure (IOP) generates stress and strains in the laminar cribrosa and sclera, which may affect the development and progression of glaucoma. Scleral stiffness and material components have changed under elevated IOP.
Chen Qiu +17 more
doaj +1 more source

