Results 41 to 50 of about 48,334 (227)

Biomechanical Impact of the Sclera on Corneal Deformation Response to an Air-Puff: A Finite-Element Study

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Aim or Purpose: To describe the effect of varying scleral stiffness on the biomechanical deformation response of the cornea under air-puff loading via a finite-element (FE) model.Methods: A two-dimensional axisymmetric stationary FE model of the whole ...
B. Audrey Nguyen   +4 more
doaj   +1 more source

Electronics‐Free Visual Monitoring of Dry Eye Disease‐Related Tear Biomarkers Using Smart Scleral Lenses

open access: yesAdvanced Science, EarlyView.
An electronics‐free smart scleral lens passively monitors dry eye disease‐related tear biomarkers through colorimetric sensing of chloride, pH, and ocular surface temperature. Smartphone‐assisted image analysis enables quantitative interpretation, providing a simple, non‐invasive strategy for ocular health monitoring without integrated electronics ...
Ziheng Wang   +15 more
wiley   +1 more source

Quantitative structural organization of the sclera in chicks after deprivation myopia measured with second harmonic generation microscopy

open access: yesFrontiers in Medicine
Visual deprivation causes enhanced eye growth and the development of myopia, which is associated with a change in the arrangement of collagen fibers within the sclera.
Juan M. Bueno   +3 more
doaj   +1 more source

Response of the anterior sclera to accommodation in myopes and emmetropes [PDF]

open access: yes, 2016
• The biomechanical properties of the sclera are documented to be altered in eyes with myopia, with the myopic sclera thought to be more susceptible to deformation from otherwise normal ocular forces.\ud \ud • The close anatomical and functional ...
Read, Scott A.   +3 more
core  

Innovative PLA or PCL‐Based Ocular Implants Obtained From Tape Casting or Electrospinning for Sustained‐Release Dexamethasone

open access: yesJournal of Applied Polymer Science, EarlyView.
PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski   +6 more
wiley   +1 more source

Understanding the spacing of placodes in the eye: A comparative study across age and species

open access: yesThe Anatomical Record, EarlyView.
Abstract The conjunctival placodes of the avian eye form in an intriguing and conserved sequence in a circular annulus around the cornea. These 13–16 placodes develop into papillae that are essential for inducing underlying intramembranous flat bones, known as scleral ossicles, which form an important part of the ocular skeleton.
Florence Joseph   +1 more
wiley   +1 more source

Porcine sclera dissected by scalpel blades.

open access: yes, 2013
Strips in the lower and upper sides of the figure are peripapillary sclera and sclera near the limbus, respectively. The four strips of sclera between them were used for the measurement.
Yiheng Lim (308441)   +8 more
core   +1 more source

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

open access: yesSensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa   +5 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

open access: yesVIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf   +5 more
wiley   +1 more source

The Dynamic Scleral Extracellular Matrix Alterations in Chronic Ocular Hypertension Model of Rats

open access: yesFrontiers in Physiology, 2020
Intraocular pressure (IOP) generates stress and strains in the laminar cribrosa and sclera, which may affect the development and progression of glaucoma. Scleral stiffness and material components have changed under elevated IOP.
Chen Qiu   +17 more
doaj   +1 more source

Home - About - Disclaimer - Privacy