Results 131 to 140 of about 27,956 (253)

Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report

open access: yesJournal of Clinical Periodontology, Volume 53, Issue 7, Page 1068-1099, July 2026.
ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple   +30 more
wiley   +1 more source

Recommendations for Arterial Blood Gas Collection in Intensive Care: Scoping Review

open access: yesJournal of Clinical Nursing, Volume 35, Issue 7, Page 2952-2965, July 2026.
ABSTRACT Objectives To map and synthesise the main recommendations for arterial blood gas (ABG) collection in intensive care units (ICUs). Design A scoping review was conducted according to the PRISMA‐ScR Checklist, supported with The PAGER framework and guided by the Joanna Briggs Institute methodology to ensure methodological rigour and analytical ...
Laura Lima Souza   +8 more
wiley   +1 more source

Interstitial lung disease in anti-U1RNP systemic sclerosis patients: A European Scleroderma Trials and Research analysis

open access: yes
Background: Interstitial lung disease is the leading cause of morbidity and mortality in systemic sclerosis, but it is characterized by significant heterogeneity in patient outcomes. So far, little is known about the influence of anti-U1RNP antibodies on
Launay, David   +8 more
core   +1 more source

A cross-sectional comparison of three self-reported functional indices in scleroderma

open access: yes, 2003
Objectives. In scleroderma, outcome measures such as skin score provide only limited information about the functional impact of the disease. The requirement for validated and convenient instruments that reliably reflect disease morbidity is now ...
Black, C. M.   +5 more
core   +1 more source

Provenance legacies override species effects in shaping oak rhizosphere microbiomes and metabolomes

open access: yesNew Phytologist, Volume 251, Issue 1, Page 488-504, July 2026.
Graphical representation of experimental setup. Quercus spp. seeds were collected at two origins: upper Rhine basin (URB) and north German lowland (NGL). Summary As climate change drives more frequent drought‐heat extremes, selecting drought‐tolerant trees is crucial for future forest resilience. However, the role of tree–microbial associations remains
Sebastian Bibinger   +9 more
wiley   +1 more source

Scleroderma, a sign of aging

open access: yes, 2017
Hutchinson-Gilford progeria syndrome (HGPS) is regarded as a model for aging. Moreover, the mutant protein accumulating in progeria is to some extent also found in healthy aged individuals.
Verstraeten, V. L.R.M.
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, Volume 16, Issue 6, Page 1048-1059, June 2026.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Systemic sclerosis in Egyptian population with emphasis on clinical and nailfold capillaroscopic features

open access: yesScientific Reports
To describe various demographic, clinical, laboratory, and capillaroscopic features of Egyptian patients with systemic sclerosis (SSc) and to explore the relation between various capillaroscopic features and internal organ involvement as well as other ...
Amira Elsonbaty   +11 more
doaj   +1 more source

A Cooperative Release of Mitochondrial DNA From Platelets and Neutrophils Drives an Interferon Signature in Systemic Sclerosis

open access: yesArthritis &Rheumatology, Volume 78, Issue 6, Page 1281-1293, June 2026.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis   +9 more
wiley   +1 more source

Long‐Term Outcomes of Reduced‐Intensity Conditioning Hematopoietic Stem Cell Transplantation for Patients With Systemic Sclerosis With Impaired Cardiac Function

open access: yesArthritis &Rheumatology, Volume 78, Issue 6, Page 1294-1305, June 2026.
Objective High‐intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced systemic sclerosis (SSc). The role of reduced‐intensity conditioning (RIC) before AHSCT in this population remains unclear.
Yonatan Lean   +4 more
wiley   +1 more source

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