Results 41 to 50 of about 10,224,515 (204)

Treatment of scleroderma by TCM

, 2010
Scleroderma is a rare persistent hardening and contraction of the body’s connective tissue, which often affect any organ, including the skin, heart, kidney, lung or oesophageal.
Yang Xiang (35912)
core   +5 more sources

Molecular subsets in the gene expression signatures of scleroderma skin. [PDF]

PLoS ONE, 2008
Scleroderma is a clinically heterogeneous disease with a complex phenotype. The disease is characterized by vascular dysfunction, tissue fibrosis, internal organ dysfunction, and immune dysfunction resulting in autoantibody production.We analyzed the ...
Ausra Milano, Sarah A Pendergrass, Jennifer L Sargent, Lacy K George, Timothy H McCalmont, M Kari Connolly, Michael L Whitfield   +6 more
doaj   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Estudo de associação entre anticorpos anticardiolipinas e fenômenos vasculares periféricos em pacientes com esclerodermia sistêmica Study about the association between anticardiolipin antibodies and peripheral vascular phenomena in patients suffering from systemic scleroderma

Anais Brasileiros de Dermatologia, 2010
Isquemia é comum em esclerodermia sistêmica e é causada por vasoespasmo e trombose. As autoras analisaram a associação de eventos vasculares periféricos e anticorpos anticardiolipinas (aCl) em 54 esclerodérmicos.
Ana Paula Torres Liberati, Camila Ferrari Ribeiro, Thelma Skare   +2 more
doaj   +1 more source

Application of an iPSC‐Derived Organoid Model for Localized Scleroderma Therapy

Advanced Science, 2022
Localized scleroderma (LoS) is a rare chronic disease with extensive tissue fibrosis, inflammatory infiltration, microvascular alterations, and epidermal appendage lesions.
Jie Ma, Wei Li, Ruiyuan Cao, Dunqin Gao, Qiyu Zhang, Xiao Li, Biyou Li, Luye Lv, Mansheng Li, Junyi Jiang, Yujie Wang, Jun Li, Zhihong Wu, Yunping Zhu, Wu Zhong, Shuyang Zhang, Ling Leng   +16 more
doaj   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Optimization of Scleroderma spore inoculum for Eucalyptus nurseries in China [PDF]

, 2006
Scleroderma, a genus of ectomycorrhizal (ECM) fungi, is often associated with trees in disturbed habitats and is therefore considered to be suitable for use in plantation forestry.
Chen, Yinglong
core  

Autoanticorpos em esclerodermia e sua associação ao perfil clínico da doença: estudo em 66 pacientes do sul do Brasil Autoantibodies in scleroderma and their association with the clinical profile of the disease: a study of 66 patients from southern Brazil

Anais Brasileiros de Dermatologia, 2011
FUNDAMENTOS: A esclerodermia é uma colagenose relativamente rara, cujo perfil de autoanticorpos está associado a diferentes manifestações clínicas. A prevalência de autoanticorpos na esclerodermia sofre influência racial e genética.
Thelma Larocca Skare, Adriano Erlon Fonseca, Alan Campos Luciano, Pedro Ming Azevedo   +3 more
doaj   +1 more source

Non-cirrhotic Portal Hypertension as the Initial Presentation of Limited Cutaneous Scleroderma: A Case Report

Journal of Investigative Medicine High Impact Case Reports, 2023
Systemic sclerosis (SSc) is an autoimmune disease characterized by progressive skin fibrosis. It has 2 main clinical subtypes—diffuse cutaneous scleroderma and limited cutaneous scleroderma. Non-cirrhotic portal hypertension (NCPH) is defined as presence
Asif Ali Hitawala MD, Christopher Redmond MD, Edward W. Cowen MD, MHSc, David E. Kleiner MD, PhD, Sarfaraz Hasni MD, Theo Heller MD   +5 more
doaj   +1 more source