Results 51 to 60 of about 26,940 (220)

Limited Cutaneous Scleroderma-Related Pulmonary Arterial Hypertension — a Case Report

Journal of Interdisciplinary Medicine, 2016
Background: Pulmonary hypertension (PH), defined by mean pulmonary arterial pressure (PAPm) ≥25 mm Hg, can lead to increasing pulmonary vascular resistance, which eventually results in right ventricle failure.
Ţilea Ioan, Bocicor Elena Andreea, Gal Codruţa Maria, Varga Andreea   +3 more
doaj   +1 more source

Barriers to care in juvenile localized and systemic scleroderma: an exploratory survey study of caregivers’ perspectives

Pediatric Rheumatology Online Journal, 2023
Background Juvenile localized scleroderma (LS) and systemic sclerosis (SSc) are rare pediatric conditions often associated with severe morbidities. Delays in diagnosis are common, increasing the risk for permanent damage and worse outcomes.
Leigh A. Stubbs, Andrew M. Ferry, Danielle Guffey, Christina Loccke, Erin Moriarty Wade, Pamela Pour, Kaveh Ardalan, Peter Chira, Ingrid M. Ganske, Daniel Glaser, Gloria Higgins, Nadia Luca, Katharine F. Moore, Vidya Sivaraman, Katie Stewart, Natalia Vasquez-Canizares, Raegan D. Hunt, Renata S. Maricevich, Kathryn S. Torok, Suzanne C. Li, Childhood Arthritis, Rheumatology Research Alliance (CARRA) Scleroderma Workgroup   +20 more
doaj   +1 more source

Physical Limitations of Scleroderma- A Personal Perspective

Academic Medicine & Surgery
Scleroderma, like many misunderstood chronic diseases, put a tremendous burden on both the patient and their family. In this deeply personal narrative, the first author describes the impact of scleroderma on her family.
Reema Adusumilli, Sydney Vaughn
openaire   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Clinical Presentation and Long-Term Outcomes of Systemic Sclerosis Portuguese Patients from a Single Centre Cohort: A EUSTAR Registration Initiative

Acta Médica Portuguesa, 2018
Introduction: Systemic sclerosis is a complex disorder that requires systematic screening. Our objective is to report the European Scleroderma Trials and Research group centre affiliation and its impact in our clinical practice. Material and Methods: The
Carolina Vidal, Carina Ruano, Vera Bernardino, Pedro Lavado Carreira, Ana Lladó, Maria Céu Santos, Heidi Gruner, António Panarra, Nuno Riso, Maria Francisca Moraes-Fontes   +9 more
doaj   +1 more source

Collalysin in therapy of patients with limited scleroderma

Kazan medical journal, 1986
In the pathogenesis of scleroderma an essential role is played by intensive collagen biosynthesis, which causes the development of fibrotic-sclerotic lesions. In this connection, it is pathogenetically substantiated the use of agents, the effect of which is aimed at decreasing the synthesis and increasing the catabolism of collagen.
openaire   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Can home rehabilitation impact impulse oscillometry and lung ultrasound findings in patients with scleroderma-associated interstitial lung disease? A pilot study

BMC Research Notes, 2022
Objective Exercise has been demonstrated to be beneficial for improving physical capacity and quality of life in people with scleroderma, although knowledge of its impact on the respiratory system is limited.
Samantha Gomes de Alegria, Patrícia Frascari Litrento, Iasmim de Oliveira Farias, Thiago Thomaz Mafort, Agnaldo José Lopes   +4 more
doaj   +1 more source

Determinants of Body Mass Index in Early Systemic Sclerosis: Implications for Nutritional Risk Stratification

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla, Meng Zhang, Bingrui Chen, Claudia Pedroza, Brian Skaug, Maureen Mayes, Michael Hughes, Shervin Assassi, Zsuzsanna H. McMahan   +8 more
wiley   +1 more source

Increased prevalence of anti-thyroid antibodies in patients with limited scleroderma

Scandinavian Journal of Rheumatology, 2011
Thyroid dysfunction in the setting of systemic sclerosis (SSc) has been described previously. We aimed to determine the prevalence of anti-thyroid antibodies (ATA) in a large SSc cohort and to ascertain whether they are associated with distinct clinical phenotypes.A total of 138 patients with SSc [46 with diffuse (dSSc) and 92 with limited scleroderma (
Danielides, S., Mavragani, C.P., Katsakoulas, I., Zintzaras, E., Drosos, A.A., Vlachoyiannopoulos, P.G., Moutsopoulos, H.M.   +6 more
openaire   +4 more sources