Results 91 to 100 of about 1,472,132 (249)

Coexistence of systemic and localized scleroderma: a systematic literature review and observational cohort study.

open access: yesRheumatology, 2020
OBJECTIVE SSc and localized sclerosis (LoS) are considered clinically distinct entities. We describe herein the coexistence of SSc and LoS by both a systematic literature review and an observational cohort study of unselected SSc patients.
A. Vanhaecke   +8 more
semanticscholar   +1 more source

Cancer Risk in Patients With Systemic Sclerosis: A Nationwide Cohort Study in South Korea 2004 to 2021

open access: yesArthritis Care &Research, Volume 77, Issue 12, Page 1466-1473, December 2025.
Objective Systemic sclerosis (SSc) is a rare autoimmune disease characterized by tissue fibrosis, vasculopathy, and immune dysregulation. Our objectives were to quantify the overall and site‐specific cancer risks in patients with SSc compared to the general population, examine temporal trends in cancer incidence following SSc diagnosis, and explore ...
Jihyun Na   +4 more
wiley   +1 more source

Clinical case of morphea associated with a malignant process with extensive skin lesions, which debuted against the background of taking anti-gouty remedy

open access: yesЛечащий Врач
Background. Localized scleroderma may be associated with a malignant process occurring in the body. The onset of scleroderma does not always coincide with the onset of clinical manifestations of oncology.
P. O. Kazakova
doaj   +1 more source

Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem Cells

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.
Vascularized skin organoids are developed from human induced pluripotent stem cells and contain macrophages, Langerhans cells, and neutrophils. Vascularized skin organoids offer a transformative platform to model skin biology and enable mechanistic investigations of inflammatory and hematologic skin disorders.
Mitchell Mostina   +9 more
wiley   +1 more source

The lens as a model for fibrotic disease [PDF]

open access: yes, 2011
Fibrosis affects multiple organs and is associated with hyperproliferation, cell transdifferentiation, matrix modification and contraction. It is therefore essential to discover the key drivers of fibrotic events, which in turn will facilitate the ...
Dawes, LJ, Eldred, JA, Wormstone, IM
core   +2 more sources

Case Report: Exacerbation after fat grafting in patients with active localized scleroderma

open access: yesFrontiers in Surgery
BackgroundThe application of autologous fat transplantation in facial lesions of patients with localized scleroderma (LoS) has been reported in recent years.ObjectiveThe authors report a case of worsening of active localized scleroderma after autologous ...
Shunxin Han   +3 more
doaj   +1 more source

The role of Borrelia burgdorferi infection in scleroderma

open access: yesRheumatology, 2014
Borrelia burgdorferi , a Gram-negative, spiral-shaped bacterium transmitted to humans via tick bites, is the etiologic agent of borreliosis (Lyme disease) with diverse clinical manifestations. There are several types of pathological lesions in the course
Żaneta Smoleńska   +3 more
doaj   +1 more source

Localized scleroderma in a newborn (case report) [PDF]

open access: yesРМЖ. Мать и дитя, 2022
N.I. Akhmina1, P.S. Utkin2, M.P. Shalatonin3, Zh.L. Chabaidze1, A.A. Dement’ev1, A.L. Zaplatnikov1 1Russian Medical Academy of Continuous Professional Education, Moscow,   Russian Federation 2Children’s Infectious Clinical Hospital
N.I. Akhmina   +5 more
doaj  

How I explore ... the skin functional involvement in scleroderma [PDF]

open access: yes, 2013
peer reviewedScleroderma refers to distinct clinical presentations sharing in common a sclerotic process most often clinically obvious on the skin. The involvement possibly affects the skin alone in morphea or in combination with internal lesions in ...
Andre, B.   +6 more
core  

Parry-Romberg syndrome: A case with a possible association with lyme disease [PDF]

open access: yes, 2015
Parry-Romberg syndrome is an acquired slowly progressive disease characterized by an atrophy mostly involving half of the face. The pathogenesis of this disfiguring condition is still controversial.
Di Meo, N.   +4 more
core   +2 more sources

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