Results 121 to 130 of about 1,415,478 (254)

Сучасні аспекти патогенетичної терапії хворих на склеродермію. Огляд літератури [PDF]

open access: yes, 2015
Дані літератури свідчать, що традиційні лікарські препарати у хворих на склеродермію ефективні далеко не завжди; багато з них спричиняють різні побічні реакції, що обумовлює пошук принципово нових терапевтичних технологій, у тому числі – з використанням ...
Горбунцов, В.В.   +2 more
core  

The Role of Abatacept on Inflammation and Fibrosis in Hypochlorous Acid‐Induced Fibrosis Mice

open access: yesInternational Journal of Rheumatic Diseases, Volume 28, Issue 5, May 2025.
ABSTRACT Aim To investigate the effect of abatacept in the hypochlorous acid (HCLO)‐induced fibrosis model and to analyze changes in immune cell fractions within the abatacept‐treated early diffuse systemic sclerosis (SSc) cohort. Methods Fibrosis was induced in BALB/c mice by subcutaneous injection of HCLO, and abatacept was injected intraperitoneally
Bingying Dai   +14 more
wiley   +1 more source

Photodynamic Therapy for Granuloma Annulare: More than a Shot in the Dark [PDF]

open access: yes, 2008
Granuloma annulare (GA) is a benign granulomatous and inflammatory skin disorder. The pathogenesis remains enigmatic and convincingly effective treatment options are not available.
Berking, Carola   +5 more
core   +1 more source

Reliability of LoSCAT score for activity and tissue damage assessment in a large cohort of patients with Juvenile Localized Scleroderma

open access: yesPediatric Rheumatology Online Journal, 2018
Objectives To assess reliability of the two indexes of Localized Scleroderma Cutaneous Assessment Tool (LoSCAT), the modified Localized Scleroderma Skin Severity Index (mLoSSI) and the Localized Scleroderma Skin Damage Index (LoSDI), when applied by ...
Anna Agazzi   +4 more
doaj   +1 more source

A Patient with Localized Scleroderma Successfully Treated with Etretinate

open access: yesCase Reports in Dermatology, 2014
There are several treatment methods for localized scleroderma, but treatment is difficult when the lesion is widely distributed. We encountered a case who was treated successfully with etretinate, a vitamin A derivative.
Tomoko Shima   +3 more
doaj   +1 more source

Baseline Description of the Juvenile Localized Scleroderma Subgroup From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry

open access: yesACR Open Rheumatology, 2019
Localized scleroderma (LS) is a chronic inflammatory and fibrosing skin disorder. We present baseline data on the juvenile LS (jLS) cohort from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry, a multicenter ...
E. Wu   +5 more
semanticscholar   +1 more source

A proposed scoring system for assessing the severity of actinic keratosis on the head: actinic keratosis area and severity index [PDF]

open access: yes, 2017
Background: Actinic keratosis (AK) severity is currently evaluated by subjective assessment of patients. Objectives: To develop and perform an initial pilot validation of a new easy-to-use quantitative tool for assessing AK severity on the head ...
Arkachaisri   +27 more
core   +1 more source

Иммуногистохимический профиль пораженной кожи при системной склеродермии [PDF]

open access: yes, 2010
З метою виявлення імуногістохімічних особливостей стану дерми і епідермісу при системній склеродермії було проведено дослідження маркерів: CD3, CD8, CD20, CD79б, CD68, CD1б, CD34, CD105, aSMA, віментин, eNOS, Ki67, колаген IV, bcl2, каспаза 3.
Романенко, К.В.
core  

Identification of fetal DNA and cells in skin lesions from women with systemic sclerosis [PDF]

open access: yes, 1998
BACKGROUND: Systemic sclerosis is a disease of unknown origin which often occurs in women after their childbearing years. It has many clinical and histopathological similarities to chronic graft-versus-host disease.
Appleton AL   +15 more
core   +2 more sources

MicroRNA in localized scleroderma: a review of literature

open access: yesArchives of Dermatological Research, 2019
Localized scleroderma (LoSc) is rare connective tissue disease that manifests with inflammation and fibrosis of the skin. Depending on the LoSc subtype, adjacent structures such as subcutaneous tissue, fascia, muscles, bones may be affected. The hallmark
Katarzyna Wolska-Gawron   +2 more
semanticscholar   +1 more source

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