Results 31 to 40 of about 1,472,132 (249)

Familial localized scleroderma with paediatric onset: a review

Advances in Dermatology and Allergology, 2021
Localized scleroderma is an inflammatory disease causing sclerosis of the skin. The aetiology and pathogenesis of localized scleroderma remain unclear. Localized scleroderma is considered a genetically driven disease. It is not well understood if genetic
Ida Yurtsever, Małgorzata Łukomska, P. Sobolewski, E. Szymańska, W. Owczarek, I. Walecka   +5 more
semanticscholar   +1 more source

Association between Localized Scleroderma Cutaneous Assessment Tool and clinicopathologic characteristics in patients with morphea

Turkderm Turkish Archives of Dermatology and Venereology, 2022
Background and Design: Morphea is also known as localized scleroderma. It is a rare autoimmune skin disease characterized by inflammation and sclerosis in the dermis and sometimes in the subcutaneous tissue.
Yıldız Gürsel Ürün, Elif Usturalı Keskin   +1 more
doaj   +1 more source

Hyperpigmented lesions with acquired atrophy following Blaschko lines in a patient with diagnosed with localized scleroderma

Boletín Médico del Hospital Infantil de México, 2021
Background: Linear atrophoderma of Moulin (LAM) is a dermatosis that affects children and adolescents characterized by hyperpigmented and atrophic linear lesions following Blaschko lines. So far, less than 50 cases have been published. Therefore, it is a
Eduardo Marín-Hernández, Belén Suárez-Frías, Alicia G. Siordia Reyes   +2 more
doaj   +1 more source

PPAR? Downregulation by TGF in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis [PDF]

, 2010
The nuclear orphan receptor peroxisome proliferator-activated receptor-gamma (PPAR-γ) is expressed in multiple cell types in addition to adipocytes. Upon its activation by natural ligands such as fatty acids and eicosanoids, or by synthetic agonists such
A Galli, A Kis, A Milano, AK Ghosh, AK Ghosh, AK Ghosh, AK Ghosh, Asish K. Ghosh, BC Willis, BM Psaty, C Beyer, C Dong, Carol Feghali-Bostwick, DA Culver, ED Rosen, ED Rosen, F Verrecchia, F Zheng, G Lakos, H Ha, HA Burgess, J Berger, J Varga, J Varga, JE Milam, Jennifer L. Sargent, JL Sargent, John Varga, Joy Sturtevant, JT Tan, Jun Wei, KA Longo, Kazuhiro Komura, KM Hong, L Fajas, L Yang, LS Higgins, M Dudas, M Kapoor, M Kapoor, M Lehrke, M Trojanowska, M Wu, Manu Jain, MF Simon, Michael L. Whitfield, Minghua Wu, OA Gressner, P Karnik, P Tontonoz, Qi-Quan Huang, R Fleischmajer, S Dennler, S Kim, S Sonnylal, S Zheng, SE Ross, SH Liu, SJ Chen, SZ Duan, T Kawai, T Miyahara, T Shiomi, TM McIntyre, V Zoete, W Yuan, X Li, X Liu, X Shi-wen, X Tan, Y Mori, Y Mori, Y Park, Y Shi, Y Wang, Z Yun   +75 more
core   +4 more sources

Localized scleroderma en coup de sabre in the Neurology Clinic [PDF]

, 2016
Background: Localized scleroderma en coup de sabre (LScs) is a form of localized scleroderma thought to be an autoimmune disorder. Central nervous system involvement is not rare and neurological manifestations include seizures, focal neurological ...
Cerqueira, João José, Fernandes, João Soares, Lourenço, Esmeralda, Macedo, Cristiana, Maré, Ricardo, Pereira, João, Pinho, João, Rocha, João, Sousa, Filipa   +8 more
core   +1 more source

Nailfold capillaroscopy in children and adolescents with rheumatic diseases [PDF]

, 2012
OBJECTIVE: To assess nailfold capillaroscopy in children and adolescents with autoimmune rheumatic diseases (juvenile idiopathic arthritis, systemic lupus erythematosus, juvenile dermatomyositis, scleroderma and mixed connective tissue disease) and ...
Hilário, Maria Odete Esteves, Len, Claudio Arnaldo, Piotto, Daniela Gerent Petry, Terreri, Maria Teresa Ramos Ascensão   +3 more
core   +3 more sources

Persistent Vascular Collagen Accumulation Alters Hemodynamic Recovery from Chronic Hypoxia [PDF]

, 2012
Pulmonary arterial hypertension (PAH) is caused by narrowing and stiffening of the pulmonary arteries that increase pulmonary vascular impedance (PVZ). In particular, small arteries narrow and large arteries stiffen. Large pulmonary artery (PA) stiffness
Chesler, Naomi C., Hacker, Timothy A., Molthen, Robert C., Roldan-Alzate, Alejandro, Tabima, Diana M., Wang, Zhijie   +5 more
core   +2 more sources

Scleroderma and dentistry: Two case reports [PDF]

, 2016
© 2016 The Author(s).Background: Scleroderma is a chronic connective tissue disorder with unknown etiology. It is characterized by excessive deposition of extracellular matrix in the connective tissues causing vascular disturbances which can result in ...
Bornstein, Michael M., Dixit, Shantanu, Kalkur, Chaithra, Melton, Fred, Sattur, Atul P.   +4 more
core   +1 more source

Localized scleroderma: A rare clinical entity

Journal of Indian Academy of Oral Medicine and Radiology, 2014
Localized Scleroderma (LS), which is also referred to as morphea, is an inflammatory disease that leads to diffuse or localized fibrotic and atrophic skin hardening.
Ranjana Garg, Swati Dhingra, Ravneet Arora   +2 more
doaj   +1 more source

The Plastic Surgery for Localized Scleroderma: Progress in Diagnosis and Treatment and Opinions from Peking Union Medical College Hospital

Xiehe Yixue Zazhi, 2022
Localized scleroderma is a rare auto-immune disorder characterized by inflammation and fibrosis of the skin and subcutaneous fat in the affected area, leaving aesthetic impairment to the patients.Such patients often seek plastic surgery for the treatment.
WANG Chenyu, LONG Xiao, ZENG Ang, HUANG Jiuzuo, WANG Xiaojun   +4 more
doaj   +1 more source