Results 31 to 40 of about 1,415,478 (254)

Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens. [PDF]

open access: yesPLoS ONE, 2018
In this study, we developed a series of synthetic oligonucleotides that allowed us to investigate the details on the antigen recognition by autoimmune antibodies in localized scleroderma subjects.
Simone Samuelsen   +4 more
doaj   +1 more source

Systemic sclerosis with keloidal nodules [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2013
Nodular sclerosis is a rare form of presentation related to both systemic and localized forms of scleroderma. We describe the case of a patient with nodular sclerosis in order to alert the medical community to recognize this entity.
Bárbara Stadler   +4 more
doaj   +1 more source

The Anti-Fibrotic Effect of Cold Atmospheric Plasma on Localized Scleroderma In Vitro and In Vivo

open access: yesBiomedicines, 2021
Cold Atmospheric Plasma (CAP) has shown promising results in the treatment of various skin diseases. The therapeutic effect of CAP on localized scleroderma (LS), however, has not yet been evaluated.
S. Arndt   +4 more
semanticscholar   +1 more source

Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study

open access: yesClinical, Cosmetic and Investigational Dermatology, 2021
Background Localized scleroderma (LoS) is an inflammatory fibrosing disease of the connective tissue, whose esthetic sequelae are atrophic skin lesions with hyperpigmentation.
M. Szczepanek   +2 more
semanticscholar   +1 more source

No Evidence for Borrelia burgdorferi-Specific DNA in Lesions of Localized Scleroderma [PDF]

open access: yes, 1995
A possible association of Borrelia burgdorferi with localized scleroderma is currently the focus of intense research and discussion. Skin biopsies from 30 patients with localized scleroderma (28 of the plaque type/morphea; two linear scleroderma) were ...
Meurer, Michael   +5 more
core   +1 more source

Familial localized scleroderma with paediatric onset: a review

open access: yesAdvances in Dermatology and Allergology, 2021
Localized scleroderma is an inflammatory disease causing sclerosis of the skin. The aetiology and pathogenesis of localized scleroderma remain unclear. Localized scleroderma is considered a genetically driven disease. It is not well understood if genetic
Ida Yurtsever   +5 more
semanticscholar   +1 more source

Localized scleroderma – current treatment options

open access: yesPrzegląd Dermatologiczny, 2017
Localized scleroderma (morphea) is a connective tissue disease that affects the skin, subcutaneous tissue and underlying tissues including the fasciae, muscles and bones. The treatment of localized scleroderma depends on the clinical form of the disease,
Katarzyna Wolska-Gawron   +2 more
doaj   +1 more source

Localized scleroderma secondary to mixed connective tissue disease during abatacept therapy

open access: yesJournal of Cutaneous Immunology and Allergy, 2022
A 47‐year‐old woman with mixed connective tissue disease was treated with abatacept. After 2 months, a 3‐cm depression with atrophied surface was observed on her back, which had histopathological consistent with the symptoms of localized scleroderma ...
Sayuko Nagaoka   +2 more
doaj   +1 more source

Oxidative stress in the pathogenesis of systemic scleroderma: An overview [PDF]

open access: yes, 2018
Systemic sclerosis (SSc) is a rare disorder of the connective tissue characterized by fibrosis of the skin, skeletal muscles and visceral organs. Additional manifestations include activation of the immune system and vascular injury. SSc causes disability
Gambardella, Lucrezia   +5 more
core   +1 more source

Association between Localized Scleroderma Cutaneous Assessment Tool and clinicopathologic characteristics in patients with morphea

open access: yesTurkderm Turkish Archives of Dermatology and Venereology, 2022
Background and Design: Morphea is also known as localized scleroderma. It is a rare autoimmune skin disease characterized by inflammation and sclerosis in the dermis and sometimes in the subcutaneous tissue.
Yıldız Gürsel Ürün   +1 more
doaj   +1 more source

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