Results 31 to 40 of about 1,480,350 (249)

PPAR? Downregulation by TGF in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis [PDF]

, 2010
The nuclear orphan receptor peroxisome proliferator-activated receptor-gamma (PPAR-γ) is expressed in multiple cell types in addition to adipocytes. Upon its activation by natural ligands such as fatty acids and eicosanoids, or by synthetic agonists such
A Galli, A Kis, A Milano, AK Ghosh, AK Ghosh, AK Ghosh, AK Ghosh, Asish K. Ghosh, BC Willis, BM Psaty, C Beyer, C Dong, Carol Feghali-Bostwick, DA Culver, ED Rosen, ED Rosen, F Verrecchia, F Zheng, G Lakos, H Ha, HA Burgess, J Berger, J Varga, J Varga, JE Milam, Jennifer L. Sargent, JL Sargent, John Varga, Joy Sturtevant, JT Tan, Jun Wei, KA Longo, Kazuhiro Komura, KM Hong, L Fajas, L Yang, LS Higgins, M Dudas, M Kapoor, M Kapoor, M Lehrke, M Trojanowska, M Wu, Manu Jain, MF Simon, Michael L. Whitfield, Minghua Wu, OA Gressner, P Karnik, P Tontonoz, Qi-Quan Huang, R Fleischmajer, S Dennler, S Kim, S Sonnylal, S Zheng, SE Ross, SH Liu, SJ Chen, SZ Duan, T Kawai, T Miyahara, T Shiomi, TM McIntyre, V Zoete, W Yuan, X Li, X Liu, X Shi-wen, X Tan, Y Mori, Y Mori, Y Park, Y Shi, Y Wang, Z Yun   +75 more
core   +4 more sources

Hyperpigmented lesions with acquired atrophy following Blaschko lines in a patient with diagnosed with localized scleroderma

Boletín Médico del Hospital Infantil de México, 2021
Background: Linear atrophoderma of Moulin (LAM) is a dermatosis that affects children and adolescents characterized by hyperpigmented and atrophic linear lesions following Blaschko lines. So far, less than 50 cases have been published. Therefore, it is a
Eduardo Marín-Hernández, Belén Suárez-Frías, Alicia G. Siordia Reyes   +2 more
doaj   +1 more source

Localized scleroderma en coup de sabre in the Neurology Clinic [PDF]

, 2016
Background: Localized scleroderma en coup de sabre (LScs) is a form of localized scleroderma thought to be an autoimmune disorder. Central nervous system involvement is not rare and neurological manifestations include seizures, focal neurological ...
Cerqueira, João José, Fernandes, João Soares, Lourenço, Esmeralda, Macedo, Cristiana, Maré, Ricardo, Pereira, João, Pinho, João, Rocha, João, Sousa, Filipa   +8 more
core   +1 more source

Scleroderma and dentistry: Two case reports [PDF]

, 2016
© 2016 The Author(s).Background: Scleroderma is a chronic connective tissue disorder with unknown etiology. It is characterized by excessive deposition of extracellular matrix in the connective tissues causing vascular disturbances which can result in ...
Bornstein, Michael M., Dixit, Shantanu, Kalkur, Chaithra, Melton, Fred, Sattur, Atul P.   +4 more
core   +1 more source

Prevalence and Clinical Characteristics of Systemic Sclerosis in Alaska Native and American Indian Peoples in Alaska. [PDF]

ACR Open Rheumatol
Objective Systemic sclerosis (SSc) is known to exhibit significant epidemiologic and clinical variation. This study aimed to describe the clinical and epidemiologic characteristics of SSc in Alaska Native and American Indian (AN/AI) individuals in Alaska.
Mehta VR, Holck P, Choromanski TL, Wilson A, Lee F, Ferucci ED.   +5 more
europepmc   +2 more sources

Nailfold capillaroscopy in children and adolescents with rheumatic diseases [PDF]

, 2012
OBJECTIVE: To assess nailfold capillaroscopy in children and adolescents with autoimmune rheumatic diseases (juvenile idiopathic arthritis, systemic lupus erythematosus, juvenile dermatomyositis, scleroderma and mixed connective tissue disease) and ...
Hilário, Maria Odete Esteves, Len, Claudio Arnaldo, Piotto, Daniela Gerent Petry, Terreri, Maria Teresa Ramos Ascensão   +3 more
core   +3 more sources

Ultrasonographic evaluation of submucosal thickness in oral submucous fibrosis patients : a cross-sectional study [PDF]

, 2018
Purpose: To evaluate the role of ultrasonography in oral submucous fibrosis (OSMF) patients. Material and methods: A total of 150 subjects were divided equally into six groups (Group I: 25 healthy subjects; Group II: 25 healthy subjects with habit; Group
Dhole, Apeksha, Dupare, Aditya
core   +1 more source

Persistent Vascular Collagen Accumulation Alters Hemodynamic Recovery from Chronic Hypoxia [PDF]

, 2012
Pulmonary arterial hypertension (PAH) is caused by narrowing and stiffening of the pulmonary arteries that increase pulmonary vascular impedance (PVZ). In particular, small arteries narrow and large arteries stiffen. Large pulmonary artery (PA) stiffness
Chesler, Naomi C., Hacker, Timothy A., Molthen, Robert C., Roldan-Alzate, Alejandro, Tabima, Diana M., Wang, Zhijie   +5 more
core   +2 more sources

Localized scleroderma: A rare clinical entity

Journal of Indian Academy of Oral Medicine and Radiology, 2014
Localized Scleroderma (LS), which is also referred to as morphea, is an inflammatory disease that leads to diffuse or localized fibrotic and atrophic skin hardening.
Ranjana Garg, Swati Dhingra, Ravneet Arora   +2 more
doaj   +1 more source

The Plastic Surgery for Localized Scleroderma: Progress in Diagnosis and Treatment and Opinions from Peking Union Medical College Hospital

Xiehe Yixue Zazhi, 2022
Localized scleroderma is a rare auto-immune disorder characterized by inflammation and fibrosis of the skin and subcutaneous fat in the affected area, leaving aesthetic impairment to the patients.Such patients often seek plastic surgery for the treatment.
WANG Chenyu, LONG Xiao, ZENG Ang, HUANG Jiuzuo, WANG Xiaojun   +4 more
doaj   +1 more source