Results 21 to 30 of about 471,570 (210)

A case of localized bullous scleroderma

Vestnik Dermatologii i Venerologii, 2017
Bullous scleroderma is a rare type of the focal form of the disease mainly affecting the skin and characterized by induration and sclerosis foci as well as subepidermal blisters containing a transparent matter.
A. L. Bakulev, E. M. Galkina, A. V. Karakaeva, M. V. Litvinenko   +3 more
doaj   +2 more sources

A Patient with Localized Scleroderma Successfully Treated with Etretinate

Case Reports in Dermatology, 2014
There are several treatment methods for localized scleroderma, but treatment is difficult when the lesion is widely distributed. We encountered a case who was treated successfully with etretinate, a vitamin A derivative.
Tomoko Shima, Yuki Yamamoto, Takaharu Ikeda, Fukumi Furukawa   +3 more
doaj   +2 more sources

Synthetic Nucleic Acid Antigens in Localized Scleroderma [PDF]

, 2023
We investigated the impact of synthetic nucleic acid antigens on the autoantibody profiles in patients with localized scleroderma, an autoimmune skin disease. Anti-DNA antibodies, including double-stranded DNA (dsDNA) and single-stranded DNA (ssDNA), are
Torok, Kathryn S., Bustos, Adrian H., Kathryn S. Torok, Jørgensen, Christian Damsgaard, Gjerdrum, Lise-Mette Rahbek, Rahbek Gjerdrum, Lise Mette, Lise-Mette Rahbek Gjerdrum, Bustos, Adrián Hernández, Kira Astakhova, Bustos, Adrian H, Jørgensen, Christian Damsgaard; id_orcid, Khatri, Sangita, Sangita Khatri, Gjerdrum, Lise Mette Rahbek, Astakhova, Kira, Adrian H. Bustos, Christian Damsgaard Jørgensen   +16 more
core   +1 more source

Hand disease in scleroderma: a clinical correlate for chronic hand transplant rejection [PDF]

, 2013
Chronic rejection remains a potential long-term consequence of hand composite tissue allotransplantation (CTA). Scleroderma has already been proposed as a model for chronic facial allograft rejection based on potential parallels of observed progression ...
Puri, A, Butler, PE, Clarke, A, Amin, K; id_orcid, Amin, K, Sivakumar, B, Denton, C   +6 more
core   +1 more source

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients [PDF]

, 2001
Patients with scleroderma receiving Iloprost as a treatment for severe Raynaud's phenomenon report a reduction in skin tightness, suggesting that this drug inhibits skin fibrosis.
Stratton, R, Thomas Haberberger, Carol M. Black, Haberberger, T, Xu Shiwen, Martini, G, Holmes, A, Alan Holmes, Andrew Leask, Shiwen, X, David Abraham, Black, CM, Leask, A, Martin, GR, Abraham, D, George R. Martin, Richard Stratton, Giorgia Martini   +17 more
core   +1 more source

Association between Localized Scleroderma Cutaneous Assessment Tool and clinicopathologic characteristics in patients with morphea

Turkderm Turkish Archives of Dermatology and Venereology, 2022
Background and Design: Morphea is also known as localized scleroderma. It is a rare autoimmune skin disease characterized by inflammation and sclerosis in the dermis and sometimes in the subcutaneous tissue.
Yıldız Gürsel Ürün, Elif Usturalı Keskin   +1 more
doaj   +1 more source

Antinuclear Antibodies in Localized Scleroderma [PDF]

Arthritis & Rheumatism, 1983
AbstractWhen HeLa cells were used as the substrate for detection by the indirect immunofluorescence method, antinuclear antibodies were demonstrated in 16 of 22 (72.7%) sera from patients with localized scleroderma. When mouse kidney sections were used, the positive rate for antinuclear antibodies was 50% (11 of 22).
K, Takehara, Y, Moroi, Y, Nakabayashi, Y, Ishibashi   +3 more
openaire   +3 more sources

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]

, 2015
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Ayuko Takahashi (789901), Barbara D. Smith (2212672), Takahashi, A, Christopher Denton, Layne, MD, Bahja Ahmed-Abdi, Ayuko Takahashi, Suki, B, Nikitorowicz-Buniak, J, Bela Suki (2212681), Bahja Ahmed-Abdi (2212675), Matthew D. Layne (364786), Markella Ponticos, Ahmed-Abdi, B, Robert Lafyatis, Markella Ponticos (2212669), Xu Shiwen (2212678), Stratton, R, Bela Suki, Barbara D Smith, Richard Stratton (776213), Joanna Nikitorowicz-Buniak (776212), Smith, BD, Christopher Denton (276245), Xu Shiwen, Lafyatis, R, David Abraham (36404), Shiwen, X, David Abraham, Abraham, D, Matthew D Layne, Ponticos, M, Denton, C, Joanna Nikitorowicz-Buniak, Robert Lafyatis (38139), Richard Stratton   +35 more
core   +1 more source

Renal perfusion in scleroderma patients assessed by microbubble-based contrast-enhanced ultrasound [PDF]

, 2012
OBJECTIVES: Renal damage is common in scleroderma. It can occur acutely or chronically. Renal reserve might already be impaired before it can be detected by laboratory findings.
Himsel, Andrea, Kleinert, Stefan, Roll, Petra, Baumgärtner, Christian, Burkhardt, Harald, Tony, Hans-Peter, Janett, Manfred, Müller, Adelheid, Baumgaertner, Christian, Jenett, Manfred, Fleck, Martin, Feuchtenberger, Martin, Mueller, Adelheid   +12 more
core   +1 more source

Mycophenolate mofetil for methotrexate-resistant juvenile localized scleroderma [PDF]

, 2021
Objectives: To investigate safety and efficacy of MMF in patients with severe or MTX-refractory juvenile localized scleroderma. Methods: Consecutive juvenile localized scleroderma patients undergoing systemic treatment were included in a retrospective ...
Martini G., Culpo R., Vittadello F., Meneghel A., Saggioro L., Zulian F.   +5 more
core   +3 more sources