Results 31 to 40 of about 9,148 (176)

Localized scleroderma: A rare clinical entity

Journal of Indian Academy of Oral Medicine and Radiology, 2014
Localized Scleroderma (LS), which is also referred to as morphea, is an inflammatory disease that leads to diffuse or localized fibrotic and atrophic skin hardening.
Ranjana Garg, Swati Dhingra, Ravneet Arora   +2 more
doaj   +1 more source

Juvenile localized scleroderma: clinical picture, diagnosis, therapeutic update (literature review and own observations)

Zdorovʹe Rebenka, 2019
Among rheumatic diseases in children, a special place belongs to juvenile localized scleroderma, which is highlighted as a separate form in the structure of scleroderma diseases and is characterized by: the onset of the disease up to 16 years, skin ...
L.F. Bogmat, V.V. Nikonova
doaj   +1 more source

Fat graft and platelet-rich plasma treatment for localized facial scleroderma

Turkish Journal of Plastic Surgery, 2021
Scleroderma is an autoimmune disorder characterized by hardening of the skin on the hands, arms, and face. Immunosuppressors, vasodilators, and physiotherapy are among the treatments for scleroderma. Although these treatments can improve quality of life,
Ali Gokkaya, Dilek Demirez, Metin Gorgu, Ertugrul Karanfil, Jehat Kizilkan, Ali Dogan   +5 more
doaj   +1 more source

Localized Scleroderma, Systemic Sclerosis and Cardiovascular Risk: A Danish Nationwide Cohort Study

Acta Dermato-Venereologica, 2017
Recent findings indicate that patients with systemic sclerosis have an increased risk of cardiovascular disease. To determine whether patients with systemic sclerosis or localized scleroderma are at increased risk of cardiovascular disease, a cohort ...
Jeanette Halskou Hesselvig, Kristian Kofoed, Jashin J. Wu, Lene Dreyer, Gunnar Gislason, Ole Ahlehoff   +5 more
doaj   +1 more source

Modern methods of a localized scleroderma diagnostics [PDF]

Саратовский научно-медицинский журнал, 2016
Localized scleroderma (LS) is a disease that is characterized by the appearance of inflammatory, sclerotic and/or atrophic changes in the affected areas of the skin and underlying tissues.
Moiseyev А.А., Utz S.R.
doaj  

CLINICAL SIGNIFICANCE OF EXTRACORPOREAL PHOTOCHEMOTHERAPY IN COMPLEX TREATMENT OF LOCALIZED SCLERODERMA

Alʹmanah Kliničeskoj Mediciny, 2016
Background: Scleroderma is an autoimmune disease with progressing lesions of connective tissue where fibrosclerotic and vascular disturbances prevail.
O. A. Fomina, A. V. Molochkov, A. V. Kil’dyushevsky   +2 more
doaj   +1 more source

Intramuscular Polydeoxyribonucleotides in Fibrotic and Atrophic Localized Scleroderma: An Explorative Prospective Cohort Study

Biomedicines, 2023
Effective options in the quiescent, scantily inflammatory phase of localized scleroderma (morphea) are lacking. A cohort study in patients with histologically confirmed fibroatrophic morphea explored the therapeutic value of the anti-dystrophic A2A ...
Maurizio Romagnuolo, Chiara Moltrasio, Angelo Valerio Marzano, Gianluca Nazzaro, Simona Muratori, Sebastiano Recalcati   +5 more
doaj   +1 more source

Morphea profunda – a case report of deep localized scleroderma with severe thorax deformity

Annales Academiae Medicae Silesiensis
Deep scleroderma is a rare form of limited scleroderma characterised by deep sclerosis that may involve the muscles, fascia, subcutaneous tissue and deep layers of the skin.
Natalia Tekiela, Agnieszka Guberniak, Karina Polak, Bartosz Miziołek, Beata Bergler-Czop   +4 more
doaj   +1 more source

Adult-onset en coup de sabre scleroderma in a patient with linear localized scleroderma profunda: A case report and literature review

SAGE Open Medical Case Reports, 2021
The en coup de sabre variant of linear scleroderma typically occurs in children. We report a unique case of adult-onset en coup de sabre scleroderma in a patient with linear localized scleroderma profunda.
Roxana Mititelu, Zainab Ridha, Lydia Ouchene, Elena Netchiporouk   +3 more
doaj   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source