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A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. Localized scleroderma typically affects the skin, with formation of patches or lines of thick and unyielding ...
C. Bangert, Andrew Kim, Heidi Jacobe
semanticscholar +1 more source
The lens as a model for fibrotic disease [PDF]
Fibrosis affects multiple organs and is associated with hyperproliferation, cell transdifferentiation, matrix modification and contraction. It is therefore essential to discover the key drivers of fibrotic events, which in turn will facilitate the ...
Dawes, LJ, Eldred, JA, Wormstone, IM
core +2 more sources
The en coup de sabre variant of linear scleroderma typically occurs in children. We report a unique case of adult-onset en coup de sabre scleroderma in a patient with linear localized scleroderma profunda.
Roxana Mititelu+3 more
doaj +1 more source
Scleroderma and dentistry: Two case reports [PDF]
© 2016 The Author(s).Background: Scleroderma is a chronic connective tissue disorder with unknown etiology. It is characterized by excessive deposition of extracellular matrix in the connective tissues causing vascular disturbances which can result in ...
Bornstein, Michael M.+4 more
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Background: Scleroderma is an autoimmune disease with progressing lesions of connective tissue where fibrosclerotic and vascular disturbances prevail.
O. A. Fomina+2 more
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Fat graft and platelet-rich plasma treatment for localized facial scleroderma
Scleroderma is an autoimmune disorder characterized by hardening of the skin on the hands, arms, and face. Immunosuppressors, vasodilators, and physiotherapy are among the treatments for scleroderma. Although these treatments can improve quality of life,
Ali Gokkaya+5 more
doaj +1 more source
Modern methods of a localized scleroderma diagnostics [PDF]
Localized scleroderma (LS) is a disease that is characterized by the appearance of inflammatory, sclerotic and/or atrophic changes in the affected areas of the skin and underlying tissues.
Moiseyev А.А., Utz S.R.
doaj
Nailfold capillaroscopy in children and adolescents with rheumatic diseases [PDF]
OBJECTIVE: To assess nailfold capillaroscopy in children and adolescents with autoimmune rheumatic diseases (juvenile idiopathic arthritis, systemic lupus erythematosus, juvenile dermatomyositis, scleroderma and mixed connective tissue disease) and ...
Hilário, Maria Odete Esteves+3 more
core +3 more sources
Histological Changes of Linear Scleroderma “en Coup de Sabre”
Introduction. Scleroderma is a chronic disease of unknown aetiology characterized by skin fibrosis and is divided into two clinical entities: localized scleroderma and systemic sclerosis.
Matoshvili M.+3 more
doaj +1 more source
Paediatric localized scleroderma is a severe inflammatory disorder associated with tissue atrophy, often leading to disability. Assessing disease activity and response to treatment has always been challenging and remains an important difficulty in ...
L. Weibel+7 more
semanticscholar +1 more source