Results 61 to 70 of about 1,425,640 (254)
Morphea profunda – a case report of deep localized scleroderma with severe thorax deformity
Deep scleroderma is a rare form of limited scleroderma characterised by deep sclerosis that may involve the muscles, fascia, subcutaneous tissue and deep layers of the skin.
Natalia Tekiela+4 more
doaj +1 more source
Paediatric localized scleroderma is a severe inflammatory disorder associated with tissue atrophy, often leading to disability. Assessing disease activity and response to treatment has always been challenging and remains an important difficulty in ...
L. Weibel+7 more
semanticscholar +1 more source
Ultrasonographic evaluation of submucosal thickness in oral submucous fibrosis patients : a cross-sectional study [PDF]
Purpose: To evaluate the role of ultrasonography in oral submucous fibrosis (OSMF) patients. Material and methods: A total of 150 subjects were divided equally into six groups (Group I: 25 healthy subjects; Group II: 25 healthy subjects with habit; Group
Dhole, Apeksha, Dupare, Aditya
core +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen+6 more
wiley +1 more source
The lens as a model for fibrotic disease [PDF]
Fibrosis affects multiple organs and is associated with hyperproliferation, cell transdifferentiation, matrix modification and contraction. It is therefore essential to discover the key drivers of fibrotic events, which in turn will facilitate the ...
Dawes, LJ, Eldred, JA, Wormstone, IM
core +2 more sources
Histological Changes of Linear Scleroderma “en Coup de Sabre”
Introduction. Scleroderma is a chronic disease of unknown aetiology characterized by skin fibrosis and is divided into two clinical entities: localized scleroderma and systemic sclerosis.
Matoshvili M.+3 more
doaj +1 more source
Evaluation of mean platelet volume in localized scleroderma [PDF]
: Background: Localized scleroderma is a chronic inflammatory skin disease characterized by sclerosis of the dermis and subcutaneous tissue. Platelets play an important role in inflammation.
Anil Gulsel Bahali+5 more
doaj +1 more source
Morphea profunda or subcutaneous (deep) morphea is a variant of localized morphea, characterized by one or more ill-defined, deep sclerotic plaque. Preferential sites are the abdomen, trunk, sacral area, or extremities.
Angelo Cassisa, Margherita Vannucchi
doaj +1 more source
Localized scleroderma (LoSc) is a rare disease manifested by an inflammation and sclerosis of the skin. The latest studies focused on glycoprotein Krebs von den Lungen-6, surfactant protein-D, chemokine ligand 18 and dipeptidylpeptidase 4 as potential ...
Katarzyna Wolska-Gawron+5 more
semanticscholar +1 more source
Mucosal‐Associated Invariant T Cells in Rheumatic Diseases
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek+7 more
wiley +1 more source