Results 71 to 80 of about 1,421,662 (159)
Scleroderma-Like Lupus Panniculitis: A Case Report and Literature Review
Clinical, Cosmetic and Investigational Dermatology, 2023 Prinpat Pinyowiwat, Suthinee Rutnin, Kumutnart Chanprapaph Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Kumutnart Chanprapaph, Division of Dermatology ...
Pinyowiwat P, Rutnin S, Chanprapaph K
doaj
Journal of Cellular and Molecular Medicine, Volume 29, Issue 14, July 2025.ABSTRACT Skin fibrosis in scleroderma is a chronic and debilitating condition that affects the quality of life of patients. In this study, we fabricated a niosomal hydrogel containing bromelain to reduce skin collagen and improve skin softness in scleroderma patients.
Hanieh Ardeshiri +5 more
wiley +1 more source
Clinical, Cosmetic and Investigational Dermatology, 2022 Jaishree Sharad Skinfiniti Aesthetic Skin and Laser Clinic, Mumbai, Maharashtra, IndiaCorrespondence: Jaishree Sharad, Skinfiniti Aesthetic Skin and Laser Clinic, 601, Prabhat Chambers, Khar West, S.V.Road, Mumbai, Maharashtra, 400052, India, Tel ...
Sharad J
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The FASEB Journal, Volume 39, Issue 12, 30 June 2025.The second messenger cyclic AMP (cAMP) dedifferentiates pathologic lung and skin myofibroblasts derived from patients with scleroderma by inhibiting the MAPK p38α. Though cAMP has anti‐fibrotic effects in fibroblasts from both organs, the cellular capacity to generate cAMP in response to the canonical stimulus prostaglandin E2 (PGE2) is substantially ...
Jared D. Baas +4 more
wiley +1 more source
Arthritis &Rheumatology, Volume 77, Issue 6, Page 740-749, June 2025.Objective Little is known on the mechanisms necessary to maintain the physiologic adult human skin integrity. This study aims to quantitatively describe anatomic changes in systemic sclerosis (SSc)–skin compared with controls and investigate the underlying mechanisms.
Sara Chenguiti Fakhouri +18 more
wiley +1 more source
Narrowing Down Key Players in Autoimmunity via Single‐Cell Multiomics
European Journal of Immunology, Volume 55, Issue 6, June 2025.This review explores how single‐cell sequencing and multiomics reveal cell states and communication networks involved in autoimmunity. We highlight insights into antigen specificity and autoreactive lymphocytes, uncovering mechanisms like molecular mimicry.
Altea Gjurgjaj, Cecilia Domínguez Conde
wiley +1 more source
Juvenile Localized Scleroderma. Questions of Treatment
Вопросы современной педиатрии, 2020 Juvenile localized scleroderma (JLS) is a group of childhood diseases with the main symptom — skin and subcutaneous structures lesions, without any organ involvement. There is active (inflammatory) and fibrotic phase in development of JLS.
Rinat K. Raupov, Mikhail M. Kostik
doaj +1 more source
JEADV Clinical Practice, Volume 4, Issue 2, Page 425-439, June 2025.Abstract Background Adjuvant immunotherapy (AIO) improved recurrence‐free survival (RFS) in patients with resected stages III–IV melanoma. Real‐world data, especially in elderly patients, as well as optimal management of patients who relpases, are still limited.
Manon Blaise +10 more
wiley +1 more source
A Patient with Localized Scleroderma Successfully Treated with Etretinate
Case Reports in Dermatology, 2014 There are several treatment methods for localized scleroderma, but treatment is difficult when the lesion is widely distributed. We encountered a case who was treated successfully with etretinate, a vitamin A derivative.
Tomoko Shima +3 more
doaj +1 more source
ACR Open Rheumatology, 2019 Localized scleroderma (LS) is a chronic inflammatory and fibrosing skin disorder. We present baseline data on the juvenile LS (jLS) cohort from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry, a multicenter ...
E. Wu +5 more
semanticscholar +1 more source