Results 101 to 110 of about 41,669 (215)

New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond

open access: yesAnnals of Neurology, Volume 98, Issue 2, Page 317-328, August 2025.
The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr.   +2 more
wiley   +1 more source

Symptoms of Oesophageal Affection in Children With Scleroderma According to Mano-Impedancemetry: A Case Series

open access: yesПедиатрическая фармакология, 2019
Background. Currently, scleroderma is a rather rare disease, including among children. Despite the growing interest of investigators in this pathology, the problem of diagnosing oesophageal affection in various forms of systemic sclerosis remains under ...
Marina Ju. Stepanyan   +3 more
doaj   +1 more source

Antifibrotic effects of specific targeting of the 5‐hydroxytryptamine 2B receptor (5‐HT2BR) in murine models and ex vivo models of scleroderma skin

open access: yesArthritis &Rheumatology, Volume 77, Issue 8, Page 1063-1076, August 2025.
Objective Systemic sclerosis (SSc) is a connective tissue disease with fibrotic remodeling of the skin and various internal organs. SSc is associated with the highest case‐specific mortality of all rheumatic autoimmune diseases with limited antifibrotic treatment options.
Thuong Trinh‐Minh   +12 more
wiley   +1 more source

Eosinophilic fasciitis (Shulman's disease): review and comparative evaluation of seven patients. [PDF]

open access: yes, 2019
OBJECTIVES: Eosinophilic fasciitis (EF) was described in 1974 by Shulman as a rare fibrosing connective tissue disease of unknown etiology. An undetermined trigger is thought to lead to the degranulation of eosinophils that interact with fibroblasts and
Cimbron, M   +3 more
core   +1 more source

A Unique Presentation of Anti-RNA Polymerase III Positive Systemic Sclerosis Sine Scleroderma

open access: yesCase Reports in Rheumatology, 2016
Systemic sclerosis is a rare autoimmune disorder with a wide spectrum of clinical manifestations and a multitude of autoantibodies that are associated with it.
Cody M. Lee   +4 more
doaj   +1 more source

Monoclonal Gammopathies of Clinical Significance—Scleromyxedema: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Scleromyxedema is an uncommon, chronic connective tissue disorder with an obscure etiology. It is distinguished by fibromyxoid skin lesions and elevated serum monoclonal immunoglobulin levels. The condition's rarity limits epidemiological data, making prevalence and incidence assessment difficult.
Shanshan Liang   +4 more
wiley   +1 more source

Systemic sclerosis: current views of its pathogenesis. [PDF]

open access: yes, 2003
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the microvasculature, and numerous cellular and humoral immune abnormalities ...
Derk, Chris T., Jimenez, Sergio A.
core   +2 more sources

Intestinal involvement in graft versus host disease in children: An overview by the ESPGHAN Gastroenterology Committee

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 2, Page 246-255, August 2025.
Abstract Graft versus host disease (GVHD) is a complication that frequently occurs after haematopoietic stem cell transplantation and concerns many children in paediatric haematology‐oncology and bone marrow transplantation departments. It can affect various organs, with the skin, gastrointestinal tract and liver being the most commonly involved.
Marina Vincent   +12 more
wiley   +1 more source

Dental Implant Therapy in Patients With Autoimmune Diseases: A Scoping Review

open access: yesClinical Oral Implants Research, Volume 36, Issue 8, Page 913-929, August 2025.
ABSTRACT Objectives The aim of this scoping review is to determine the effects of autoimmune diseases (ADs) and the agents used for treatment on dental implant survival and biologic outcomes. Material and Methods An electronic database search was performed in MEDLINE (PubMed), The Cochrane Library, and Embase on 29‐04‐2024.
Emil Hyldahl   +2 more
wiley   +1 more source

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