Results 1 to 10 of about 893,284 (261)

A rare cutaneous manifestation of systemic sclerosis

open access: yesEuropean Journal of Case Reports in Internal Medicine
A 43-year-old male with a history of intravenous drug use and alcohol consumption presented to the emergency department with three-month history of failure to thrive.
Joelle Sleiman   +3 more
doaj   +1 more source

Pathogenesis of Scleroderma (Systemic Sclerosis)

open access: yesJournal of Investigative Dermatology, 1982
Increasing interest in the vascular features of scleroderma has led to the hypothesis that the blood vessel is the major target tissue and that the endothelial cell is the principal cell target. Useful observations stemming from the vascular hypothesis include the use of microvascular abnormalities in the early detection of the patient destined to ...
openaire   +2 more sources

Emphysema formation in a never-smoker with scleroderma-related interstitial pneumonia

open access: yesRespiratory Medicine Case Reports, 2018
We report a case of pathological emphysema formation in a never-smoker with scleroderma-related interstitial pneumonia. We realized the importance of pulmonary vasculopathy causing the coexistence of emphysema and fibrosis in scleroderma.
Hideaki Yamakawa   +3 more
doaj   +1 more source

Control of Fibrosis in Systemic Scleroderma.

open access: yesJournal of Investigative Dermatology, 1993
Scleroderma is characterized by an excessive deposition of collagen in all involved organs. This is due to an overproduction of extracellular matrix (ECM) molecules following induction of gene expression, whereas there is no evidence that the composition of the connective tissue matrix is altered.
Mauch, Cornelia   +5 more
openaire   +2 more sources

A case of progressive systemic scleroderma in a patient who had COVID-19: observation using computed tomography over time

open access: yesАктуальные проблемы теоретической и клинической медицины
A clinical case of a patient with systemic scleroderma who underwent COVID-19. In systemic scleroderma, pulmonary involvement is the most common cause of death in patients is presented.
E. A. Akhmetov   +2 more
doaj   +1 more source

Juvenile localized scleroderma: a large retrospective cohort study from a tertiary care center

open access: yesPediatric Rheumatology Online Journal
Background Juvenile localized scleroderma is a rare pediatric inflammatory disease that primarily affects the skin and subcutaneous tissue but also has the potential to impact deeper tissues and can be associated with extracutaneous manifestations ...
Bugra Han Egeli   +8 more
doaj   +1 more source

Systemic Sclerosis Sine Scleroderma Manifested with Gastrointestinal Bleeding, Antiphospholipid Syndrome and Positive Anti-RNA Polymerase III Antibody: Case Report and Literature Review

open access: yesInternational Medical Case Reports Journal, 2020
Mansour Alghamdi, Stephen J Derbes Department of Medicine, Rheumatology Section, Louisiana State University School of Medicine, New Orleans, LA, USACorrespondence: Mansour AlghamdiDepartment of Medicine, Rheumatology Section, Louisiana State University ...
Alghamdi M, Derbes SJ
doaj  

A Unique Presentation of Anti-RNA Polymerase III Positive Systemic Sclerosis Sine Scleroderma

open access: yesCase Reports in Rheumatology, 2016
Systemic sclerosis is a rare autoimmune disorder with a wide spectrum of clinical manifestations and a multitude of autoantibodies that are associated with it.
Cody M. Lee   +4 more
doaj   +1 more source

Systemic sclerosis (Scleroderma) Among Adults Attending the Rheumatology Clinic of a Tertiary Institution

open access: yesAnnals of Health Research, 2016
Background: Systemic sclerosis is a multi-systemic autoimmune disorder characterised by the generation of autoantibodies, massive deposition of collagen and other matrix substances in the connective tissues and alterations of the microvasculature ...
Oguntona SA, Olatunde OA, Bakare BO
doaj  

Pesticide-induced systemic scleroderma: a case report

open access: yesКлиническая практика
BACKGROUND: Systemic sclerosis, or systemic scleroderma, is a rare autoimmune connective tissue disease. The presented clinical case highlights that taking an occupational history is essential in patients with suspected systemic connective tissue ...
Olga A. Georginova   +7 more
doaj   +1 more source

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