Results 1 to 10 of about 893,284 (261)
A rare cutaneous manifestation of systemic sclerosis
A 43-year-old male with a history of intravenous drug use and alcohol consumption presented to the emergency department with three-month history of failure to thrive.
Joelle Sleiman +3 more
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Pathogenesis of Scleroderma (Systemic Sclerosis)
Increasing interest in the vascular features of scleroderma has led to the hypothesis that the blood vessel is the major target tissue and that the endothelial cell is the principal cell target. Useful observations stemming from the vascular hypothesis include the use of microvascular abnormalities in the early detection of the patient destined to ...
openaire +2 more sources
Emphysema formation in a never-smoker with scleroderma-related interstitial pneumonia
We report a case of pathological emphysema formation in a never-smoker with scleroderma-related interstitial pneumonia. We realized the importance of pulmonary vasculopathy causing the coexistence of emphysema and fibrosis in scleroderma.
Hideaki Yamakawa +3 more
doaj +1 more source
Control of Fibrosis in Systemic Scleroderma.
Scleroderma is characterized by an excessive deposition of collagen in all involved organs. This is due to an overproduction of extracellular matrix (ECM) molecules following induction of gene expression, whereas there is no evidence that the composition of the connective tissue matrix is altered.
Mauch, Cornelia +5 more
openaire +2 more sources
A clinical case of a patient with systemic scleroderma who underwent COVID-19. In systemic scleroderma, pulmonary involvement is the most common cause of death in patients is presented.
E. A. Akhmetov +2 more
doaj +1 more source
Juvenile localized scleroderma: a large retrospective cohort study from a tertiary care center
Background Juvenile localized scleroderma is a rare pediatric inflammatory disease that primarily affects the skin and subcutaneous tissue but also has the potential to impact deeper tissues and can be associated with extracutaneous manifestations ...
Bugra Han Egeli +8 more
doaj +1 more source
Mansour Alghamdi, Stephen J Derbes Department of Medicine, Rheumatology Section, Louisiana State University School of Medicine, New Orleans, LA, USACorrespondence: Mansour AlghamdiDepartment of Medicine, Rheumatology Section, Louisiana State University ...
Alghamdi M, Derbes SJ
doaj
A Unique Presentation of Anti-RNA Polymerase III Positive Systemic Sclerosis Sine Scleroderma
Systemic sclerosis is a rare autoimmune disorder with a wide spectrum of clinical manifestations and a multitude of autoantibodies that are associated with it.
Cody M. Lee +4 more
doaj +1 more source
Background: Systemic sclerosis is a multi-systemic autoimmune disorder characterised by the generation of autoantibodies, massive deposition of collagen and other matrix substances in the connective tissues and alterations of the microvasculature ...
Oguntona SA, Olatunde OA, Bakare BO
doaj
Pesticide-induced systemic scleroderma: a case report
BACKGROUND: Systemic sclerosis, or systemic scleroderma, is a rare autoimmune connective tissue disease. The presented clinical case highlights that taking an occupational history is essential in patients with suspected systemic connective tissue ...
Olga A. Georginova +7 more
doaj +1 more source

