Results 41 to 50 of about 893,284 (261)
Genome-Wide Scan Identifies TNIP1, PSORS1C1, and RHOB As Novel Risk Loci for Systemic Sclerosis [PDF]
, 2011 Systemic sclerosis (SSc) is an orphan, complex, inflammatory disease affecting the immune system and connective tissue. SSc stands out as a severely incapacitating and life-threatening inflammatory rheumatic disease, with a largely unknown pathogenesis ...P. Amouyel, MELCHERS I, Cusi, D., Amouye, Philippe, Jerome Avouac, Melchers, Inga, Salvi Erika, Müller, Martina, ALLANORE Y, Damjanov Nemanja, Meyer Oliver, HACHULLA E, Nemanja Damjanov, Hunzelmann Nicolas, I. Melchers, H.-Erich Wichmann, Wichmann, H.-E., Ulf Müller-Ladner, Lambert, J.C., Ruiz, B., AMOUYEL P, Munnich, A., Riemekasten, Gabriella, Cracowski Jean-Luc, Distler, J.H., AVOUAC J, CONTI C, Hachulla Eric, Dupuy, Anne-Marie, Dieude, Philippe, AIRO P, Munnich Arnold, Caramaschi, Paola, Avouac, Jerome, Nicolas Hunzelmann, Inga Melchers, Lambert J. C, Allanore, Y., C. Boileau, Conti, Costanza, Diot, Elisabeth, Lambert Jean-Charles, A. M. Dupuy, O. Meyer, Yannick Allanore, Avouac, J., Martinez, Maria, Ruiz Barbara, Otylia Kowal Bielecka, Wichmann, H-Erich, Luc Letenneur, J. Avouac, P. Caramaschi, Mouthon Luc, Wipff, J., Wichmann, H.-Erich, Dieudé Philippe, C. Conti, Meyer, O., E. Hachulla, M. Müller, Mouthon, L., Arnold Munnich, Avouac Jérôme, Damjanov, Nemanja, Gabriele Valentini, Valentini, G., Müller-Ladner Ulf, Caramaschi Paola, Müller, M., Tiev, Kiet, Martinez, M., Meyer, Oliver, MARTINEZ M., Kowal-Bielecka, O., H. Erich Wichmann, Distler, Jorg, H. W., A. Munnich, Matucci-Cerinic Marco, Dupuy Anne Marie, László Czirjak, G. Valentini, DAMJANOV N, MEYER O, Kahan, Andre, Melchers Inga, RICCIERI V, Saad, M., Jorg H W Distler, Cusi Daniele, Ruiz, Barbara, Kahan André, Martina Muller, E. Salvi, WIPFF J, E. Diot, Distler J, Müller Martina, CARAMASCHI P, DIOT E, Erika Salvi, J. C. Lambert, HUNZELMANN N, Matucci-Cerinic, M., Boileau, Catherine, Dieudé, P., Airo, P., Cusi, Daniele, Riccieri, Valeria, Müller-Ladner, U., J. Wipff, L. Czirják, Distler, Jorg H. W., Hachulla, E., Czirjak, Laszlo, Czijak L, Y. Allanore, MUNNICH A, Mohamad Saad, Czirják, L., Wipff, Julien, K. Tiev, L. Letenneur, Letenneur, Luc, Maria Martinez, Conti Costanza, Airo Paolo, Kowal-Bielecka, Otylia, N. Damjanov, MÜLLER LADNER U, SALVI E, WICHMANN HE, Valentini Gabriele, Jorg H. W. Distler, Paolo Airo, DUPUY AM, Valentini G, CUSI D, MÜLLER M, Mouthon, Luc, J. L. Cracowski, Damjanov, N., LAMBERT JC, Distler Jorg H. W., H-Erich Wichmann, P. Dieudé, Diot, E., MATUCCI CERINIC, Marco, Paola Caramaschi, Valentini, Gabriele, Hachulla, Eric, Jean Luc Cracowski, Tiev Kiet, CRACOWSKI JL, Airo, Paolo, Costanza Conti, Jean-Charles Lambert, RUIZ B, Daniele Cusi, Martinez Maria, Valeria Riccieri, M. Matucci Cerinic, MATUCCI CERINIC M, Eric Hachulla, H. E. Wichmann, Lambert, Jean-Charles, Wichmann, Heinz-Erich, Tiev, K., Kiet Tiev, Catherine Boileau, MOUTHON L, Riemekasten, G., Jean Charles Lambert, L. Mouthon, Caramaschi, P., Marco Matucci-Cerinic, SAAD M, B. Ruiz, Riemekasten Gabriella, J. H. Distler, BOILEAU C, Boileau Catherine, Philippe Amouyel, Riccieri Valeria, Munnich, Arnold, Cracowski, Jean-Luc, Gabriella Riemekasten, DIEUDÉ P, N. Hunzelmann, Saad Mohamad, Letenneur Luc, Czirják László, Allanore, Yannick, Philippe Dieude, Julien Wipff, Müller-Ladner, Ulf, KOWAL BIELECKA O, LETENNEUR L, Kowal-Bielecka Otylia, Elisabeth Diot, G. Riemekasten, KAHAN A, Wichmann H.-Erich, Salvi, E., Matucci-Cerinic, Marco, Dupuy, A.M., D.M. Cusi, Oliver Meyer, U. Müller Ladner, Hunzelmann, Nicolas, Allanore Yannick, Wipff Julien, Cracowski, J.L., Saad, Mohamad, Barbara Ruiz, RIEMEKASTEN G, O. Kowal Bielecka, Conti, C., M. Martinez, Jean-Luc Cracowski, P. Airo, CZIRJÁK L, Amouyel, Philippe, Letenneur, L., Salvi, Erika, DISTLER JH, Amouyel, P., Distler, Jorg,, Luc Mouthon, V. Riccieri, Hunzelmann, N., Ulf Muller Ladner, TIEV K, Dupuy, Anne Marie, Diot Elisabeth, Kahan, A., Riccieri, V., Marco Matucci Cerinic, André Kahan, Boileau, C., M. Saad, A. Kahan, Anne Marie Dupuy, Amouyel Philippe, Otylia Kowal-Bielecka, Melchers, I. +245 morecore +2 more sourcesMultiplex cytokine analysis of dermal interstitial blister fluid defines local disease mechanisms in systemic sclerosis. [PDF]
, 2015 Clinical diversity in systemic sclerosis (SSc) reflects multifaceted pathogenesis and the effect of key growth factors or cytokines operating within a disease-specific microenvironment.Christopher P Denton, Lopez, H, Etomi, O, Korsa Khan, George R Martin, Abraham, DJ, Guerra, SG, Denton, CP, Sandra G Guerra, Xu Shiwen, David J Abraham, Bahja Ahmed Abdi, Richard J Stratton, Kristina EN Clark, Oseme Etomi, Shiwen, X, Henry Lopez, Abdi, BA, Martin, GR, Stratton, RJ, Khan, K, Clark, KE +21 morecore +1 more sourceEndothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts [PDF]
, 2004 The endothelins are a family of endothelium-derived peptides that possess a variety of functions, including vasoconstriction. Endothelin-1 (ET-1) is up-regulated during tissue repair and promotes myofibroblast contraction and migration, hence ...Abraham, DJ, du Bois, R M, Denton, CP, Black, C M, Chen, YL, Chen, Y L, Chen, Y, Shi-Wen, X., Renzoni, E.A., Denton, C P, Shi-Wen, X, Leask, A., Pearson, J D, Xu, SW, Bou-Gharios, George, du Bois, RM, Xu, S W, Dashwood, M, Denton, C.P., Bou-Gharios, G., Renzoni, E A, Pearson, JD, Chen, Y., Abraham, D.J., Abraham, D J, Renzoni, EA, Black, CM, Dashwood, M., Eastwood, M, Leask, A, Eastwood, M., Black, C.M., Pearson, J., du Bois, R., Bou-Gharios, G +34 morecore +1 more sourcePatterns of patient-reported symptoms and association with sociodemographic and systemic sclerosis disease characteristics: a scleroderma Patient-centered Intervention Network (SPIN) Cohort cross-sectional studyResearch in context
EClinicalMedicine, 2023 Summary: Background: Systemic sclerosis is a heterogenous disease in which little is known about patterns of patient-reported symptom clusters. We aimed to identify classes of individuals with similar anxiety, depression, fatigue, sleep disturbance, and Robyn K. Wojeck, Mitchell R. Knisely, Donald E. Bailey, Tamara J. Somers, Linda Kwakkenbos, Marie-Eve Carrier, Warren R. Nielson, Susan J. Bartlett, Vanessa L. Malcarne, Marie Hudson, Brooke Levis, Andrea Benedetti, Luc Mouthon, Brett D. Thombs, Susan G. Silva, Claire E. Adams, Richard S. Henry, Catherine Fortuné, Karen Gottesman, Geneviève Guillot, Laura K. Hummers, Amanda Lawrie-Jones, Maureen D. Mayes, Michelle Richard, Maureen Sauvé, Shervin Assassi, Ghassan El-Baalbaki, Kim Fligelstone, Tracy Frech, Amy Gietzen, Daphna Harel, Monique Hinchcliff, Sindhu R. Johnson, Maggie Larche, Catarina Leite, Christelle Nguyen, Karen Nielsen, Janet Pope, François Rannou, Tatiana Sofia Rodriguez-Reyna, Anne A. Schouffoer, Maria E. Suarez-Almazor, Christian Agard, Nassim Ait Abdallah, Marc André, Elana J. Bernstein, Sabine Berthier, Lyne Bissonnette, Alessandra Bruns, Patricia Carreira, Marion Casadevall, Benjamin Chaigne, Lorinda Chung, Benjamin Crichi, Christopher Denton, Robyn Domsic, James V. Dunne, Bertrand Dunogue, Regina Fare, Dominique Farge-Bancel, Paul R. Fortin, Jessica Gordon, Brigitte Granel-Rey, Aurélien Guffroy, Genevieve Gyger, Eric Hachulla, Sabrina Hoa, Alena Ikic, Suzanne Kafaja, Nader Khalidi, Kimberly Lakin, Marc Lambert, David Launay, Yvonne C. Lee, Hélène Maillard, Nancy Maltez, Joanne Manning, Isabelle Marie, Maria Martin Lopez, Thierry Martin, Ariel Masetto, François Maurier, Arsene Mekinian, Sheila Melchor Díaz, Mandana Nikpour, Louis Olagne, Vincent Poindron, Susanna Proudman, Alexis Régent, Sébastien Rivière, David Robinson, Esther Rodríguez Almazar, Sophie Roux, Perrine Smets, Vincent Sobanski, Robert Spiera, Virginia Steen, Evelyn Sutton, Carter Thorne, John Varga, Pearce Wilcox, Mara Cañedo Ayala, Vanessa Cook, Sophie Hu, Bianca Matthews, Elsa-Lynn Nassar, Marieke Alexandra Neyer, Julia Nordlund, Sabrina Provencher +108 moredoaj +1 more sourceTHE SYSTEMIC INVOLVEMENT IN SCLERODERMA [PDF]
Medical Journal of Australia, 1977 A survey was made of the systemic involvement in 38 patients with scleroderma: 33 with the acrosclerotic form (Type 1, 18, Type 2, 15) and five with the diffuse form. The study comprised inquiry about symptoms, physical examination, and the laboratory tests, such as radiological examination of chest and hands, barium swallow and meal X-ray examination, openaire +2 more sourcesSystemic Sclerosis — Scleroderma
Dermatology Online Journal, 2000 Systemic sclerosis is a clinically heterogeneous, systemic disorder which affects the connective tissue of the skin, internal organs and the walls of blood vessels. It is characterized by alterations of the microvasculature, disturbances of the immune system and by massive deposition of collagen and other matrix substances in the connective tissue ...openaire +4 more sourcesScleroderma and scleroderma-like syndromes
Frontiers in ImmunologySystemic sclerosis is a systemic connective tissue disease whose main pathophysiological mechanism is a progressive fibrosis of internal organs and skin leading to thickening and induration. Blood vessels may also be involved.Katarzyna Romanowska-Próchnicka, Martyna Dziewit, Aleksandra Lesiak, Adam Reich, Marzena Olesińska +4 moredoaj +1 more source
