Results 21 to 30 of about 893,284 (261)

Renal Involvement in Systemic Sclerosis: An Update

open access: yesKidney & Blood Pressure Research, 2020
Background: Systemic sclerosis is an immune-mediated rheumatic disease characterized by vascular abnormalities, tissue fibrosis and autoimmune phenomena.
Magdalena Chrabaszcz   +6 more
doaj   +1 more source

Localized scleroderma: clinical spectrum and therapeutic update [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis ...
Mariana Figueiroa Careta, Ricardo Romiti
doaj   +2 more sources

A case of scleroderma-like lesions as a cutaneous manifestation of carcinoid syndrome

open access: yesCurrent Problems in Cancer: Case Reports, 2022
Scleroderma-like lesions are a rare sign of carcinoid syndrome which have been associated with poor prognosis. They differ from systemic sclerosis by involving preferentially the skin in the lower limbs, lacking Raynaud's phenomenon and having no ...
João Boavida Ferreira   +5 more
doaj   +1 more source

Modern Pathogenetic Mechanisms of Systemic Scleroderma [PDF]

open access: yes, 2023
Systemic scleroderma is a chronic and often progressive autoimmune inflammation of the connective tissue, characterized by fibrosis of the skin and internal organs, widespread vascular lesions with unknown etiology, and heterogeneous clinical ...
Botirbekov Abdurashid Nazarkulovich
core   +1 more source

Cultural adaptation and validation of the scleroderma health assessment questionnaire into Arabic language

open access: yesEgyptian Rheumatology and Rehabilitation, 2023
Background Systemic sclerosis is an autoimmune multisystem disorder which affects the patients’ physical and psychological functioning. Scleroderma health assessment questionnaire used to measure physical disability in systemic sclerosis patients.
Samah Mahmoud Alian   +3 more
doaj   +1 more source

Preliminary safety and efficacy profile of prucalopride in the treatment of systemic sclerosis (SSc)-related intestinal involvement: results from the open label cross-over PROGASS study

open access: yesArthritis Research & Therapy, 2017
Background Prokinetics are used to treat enteric dismotility symptoms in systemic sclerosis (SSc) patients, but they often lack adequate efficacy. The most effective prokinetics belonging to the serotonin (5-HT4) receptor agonists class were withdrawn ...
Barbara Vigone   +8 more
doaj   +1 more source

Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group [PDF]

open access: yes, 2012
INTRODUCTION: Erectile dysfunction (ED) is common in men with systemic sclerosis (SSc) but the demographics, risk factors and treatment coverage for ED are not well known.
Smith, Vanessa   +62 more
core   +1 more source

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]

open access: yes, 2015
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Ayuko Takahashi (789901)   +35 more
core   +1 more source

Application and performance of disease activity indices proposed for patients with systemic sclerosis in an international cohort of patients with juvenile systemic sclerosis [PDF]

open access: yes, 2023
Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: the inception cohort project is supported by an unrestricted grant from the Joachim Herz Stiftung ...
Adrovic, Amra   +32 more
core   +1 more source

Refractory scleroderma renal crisis precipitated after high-dose oral corticosteroids and concurrent intravitreal injection of bevacizumab

open access: yesSAGE Open Medical Case Reports, 2020
Scleroderma renal crisis is a serious complication that can develop in certain patients with systemic sclerosis. Some risks have been identified as potential triggers of scleroderma renal crisis, including the high-dose oral corticosteroids.
Ramy M Hanna   +9 more
doaj   +1 more source

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