Prognostic Factors of Renal Involvement in Systemic Sclerosis [PDF]
, 2018 Background/Aims: Renal involvement is common in systemic sclerosis (SSc), including asymptomatic reduction of glomerular filtration rate (GFR), increased renal resistance indices, scleroderma renal crisis (SRC) and ANCA-associated vasculitis. The aim was
Barbano, Biagio +5 more
core +2 more sources
Calcinosis circumscripta of the breasts: The deeper meaning
South African Journal of Radiology, 2023 Calcinosis circumscripta involving the breasts usually hints at an underlying systemic cause, most commonly connective tissue disorders such as scleroderma or dermatomyositis.
Tanusha Sewchuran, Joel M. Kabeya
doaj +1 more source
A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]
, 2015 In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Abraham, D +11 more
core +3 more sources
Angiogenic and angiostatic factors in renal scleroderma-associated vasculopathy [PDF]
, 2017 BACKGROUND: The angiogenesis in systemic sclerosis (SSc) is impaired. An imbalance of pro-angiogenic factors and angiogenesis inhibitors has been implicated in the progression of peripheral microvascular damage, defective vascular repair and fibrosis ...
Afeltra, Antonella M. Vittoria +7 more
core +1 more source
Cerebral Sinus Thrombosis in Scleroderma: A Case Report [PDF]
Acta Medica Iranica, 2012 Scleroderma or systemic sclerosis is a multisystem disease due to excessive collagen deposition in different organs and autoimmunity by production of autoantibodies.According to previous reports, brain is rarely affected in scleroderma, howeverrecent ...
Maryam Poursadegh Fard +1 more
doaj +2 more sources
A prospective observational study of mycophenolate mofetil treatment in progressive diffuse cutaneous systemic sclerosis of recent onset. [PDF]
, 2012 OBJECTIVE: A prospective observational study of mycophenolate mofetil (MMF) treatment in patients with diffuse progressive cutaneous systemic sclerosis (SSc) of recent onset.
Jimenez, Sergio A. +3 more
core +3 more sources
Laser therapy in superficial morphea lesions – indications, limitations and therapeutic alternatives [PDF]
, 2020 Morphea or localized scleroderma is an uncommon autoimmune and inflammatory disease which affects patients of any age. Even if morphea lesions present systemic symptoms as myalgias or arthritis, it is distinct from systemic sclerosis because it does not ...
Ardeleanu, Valeriu +4 more
core +2 more sources
EClinicalMedicine, 2023 Summary: Background: Systemic sclerosis is a heterogenous disease in which little is known about patterns of patient-reported symptom clusters. We aimed to identify classes of individuals with similar anxiety, depression, fatigue, sleep disturbance, and
Robyn K. Wojeck +108 more
doaj +1 more source
Left ventricular mass and intrarenal arterial stiffness as early diagnostic markers in cardiorenal syndrome type 5 due to systemic sclerosis [PDF]
, 2016 Background: Cardiorenal syndrome type 5 (CRS-5) includes a group of conditions characterized by a simultaneous involvement of the heart and kidney in the course of a systemic disease.
AMOROSO, Antonio +11 more
core +1 more source
Systemic Sclerosis Manifesting Post-Radiotherapy: A Case Report
European Medical Journal Dermatology, 2023 Morphoea is a chronic inflammatory disease of the skin and underlying tissues, characterised by fibrosis of the skin and subcutaneous tissue without systemic involvement.
Devanshi Nimbark +2 more
doaj +1 more source