Results 111 to 120 of about 41,669 (215)
The FASEB Journal, Volume 39, Issue 13, 15 July 2025.We report the first tractable and reversible Wnt activation model in dermal adipocytes in mouse skin. Our findings demonstrate that sustained Wnt activation in mature dermal adipocytes leads to lipodystrophy, which is sufficient to induce skin fibrosis in vivo.
Qiannan Ma +10 more
wiley +1 more source
Systemic sclerosis (Scleroderma) and malignancy
Japanese Journal of Clinical Immunology, 2004 The association of malignancy with collagen diseases has been a focus of interest. Especially, relation between dermatomyositis and malignancy is well-recognized. I reviewed here about the coexistence of SSc and malignancy in literature. I would like to raise four points as characteristics of the relationship.
openaire +4 more sources
Juvenile localized scleroderma: a large retrospective cohort study from a tertiary care center
Pediatric Rheumatology Online JournalBackground Juvenile localized scleroderma is a rare pediatric inflammatory disease that primarily affects the skin and subcutaneous tissue but also has the potential to impact deeper tissues and can be associated with extracutaneous manifestations ...
Bugra Han Egeli +8 more
doaj +1 more source
Esophageal involvement in progressive systemic sclerosis
Autopsy and Case Reports, 2013 Progressive systemic sclerosis (PSSc) is a chronic disease of unknown etiology characterized by progressive, abnormal accumulation of fibrous tissue in the skin and many organs.
Stephen A. Geller +1 more
doaj +1 more source
Laser therapy in superficial morphea lesions – indications, limitations and therapeutic alternatives [PDF]
, 2020 Morphea or localized scleroderma is an uncommon autoimmune and inflammatory disease which affects patients of any age. Even if morphea lesions present systemic symptoms as myalgias or arthritis, it is distinct from systemic sclerosis because it does not ...
Ardeleanu, Valeriu +4 more
core +1 more source
Annals of Health Research, 2016 Background: Systemic sclerosis is a multi-systemic autoimmune disorder characterised by the generation of autoantibodies, massive deposition of collagen and other matrix substances in the connective tissues and alterations of the microvasculature ...
Oguntona SA, Olatunde OA, Bakare BO
doaj
Bosentan Does Not Affect Renal Resistive Index in Scleroderma/Systemic Sclerosis Patients.
Kidney Blood Press Res, 2023 Di Poi E +8 more
europepmc +1 more source
Case Reports in OphthalmologyThis is an observational case report to detail a novel case of scleroderma renal crisis presenting as bilateral exudative retinal detachments in a patient with newly diagnosed systemic sclerosis.
Rem Aziz +3 more
doaj +1 more source
Indian Journal of Rheumatology, 2017 Systemic sclerosis is a rare autoimmune connective tissue disorder characterised typically by tightening and tethering of skin. However, several other disorders are also characterised by hardening and thickening of skin.
Kaveri K Nalianda +3 more
doaj
Emphysema formation in a never-smoker with scleroderma-related interstitial pneumonia
Respiratory Medicine Case Reports, 2018 We report a case of pathological emphysema formation in a never-smoker with scleroderma-related interstitial pneumonia. We realized the importance of pulmonary vasculopathy causing the coexistence of emphysema and fibrosis in scleroderma.
Hideaki Yamakawa +3 more
doaj