Results 111 to 120 of about 55,245 (231)
Juvenile localized scleroderma: a large retrospective cohort study from a tertiary care center
Background Juvenile localized scleroderma is a rare pediatric inflammatory disease that primarily affects the skin and subcutaneous tissue but also has the potential to impact deeper tissues and can be associated with extracutaneous manifestations ...
Bugra Han Egeli +8 more
doaj +1 more source
Janus Kinase Inhibitors for the Treatment of Pediatric Morphea: A Systematic Review
ABSTRACT Morphea, also known as localized scleroderma (LoS), is an inflammatory, fibrosing dermatologic disorder of the skin and underlying tissues with associated comorbidities including joint contractures, limb‐length discrepancies, and inflammatory arthropathy occurring more commonly in children.
Alexa Moschella +2 more
wiley +1 more source
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde +6 more
wiley +1 more source
[Systemic sclerosis (scleroderma) without scleroderma].
There are two approaches toward dealing with systemic sclerosis (scleroderma) presenting with no skin involvement. According to one of these the condition is to be treated as atypical systemic sclerosis (scleroderma). With the other approach it does not make much difference whether systemic sclerosis presents with skin involvement or not.
openaire +1 more source
Abstract The phosphodiesterase‐5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug‐induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing ‘R‐on‐T’ ventricular tachycardia.
David C. Hutchings +3 more
wiley +1 more source
Background: Systemic sclerosis is a multi-systemic autoimmune disorder characterised by the generation of autoantibodies, massive deposition of collagen and other matrix substances in the connective tissues and alterations of the microvasculature ...
Oguntona SA, Olatunde OA, Bakare BO
doaj
Manifestation of morphea in a patient with myasthenia gravis under therapy with zilucoplan
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Phoebe Wellmann +3 more
wiley +1 more source
Abstract Background Studies suggest an increase in autoimmune diseases following SARS‐CoV‐2 infection and/or COVID‐19‐vaccination. We aimed to describe possible associations in Norway. Methods We used information from the emergency preparedness register for COVID‐19, BeredtC19, for all residents aged 18–64 (N = 3,450,080).
Håkon Bøås +4 more
wiley +1 more source
Mother-child histocompatibility and risk of rheumatoid arthritis and systemic lupus erythematosus among mothers. [PDF]
The study objective was to test the hypothesis that having histocompatible children increases the risk of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), possibly by contributing to the persistence of fetal cells acquired during ...
Barcellos, Lisa F +16 more
core
Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang +4 more
wiley +1 more source

