Results 11 to 20 of about 734,275 (243)

Proteomic aptamer analysis reveals serum markers that characterize preclinical systemic sclerosis (SSc) patients at risk for progression toward definite SSc

Arthritis Research & Therapy, 2023
Background The study of molecular mechanisms characterizing disease progression may be relevant to get insights into systemic sclerosis (SSc) pathogenesis and to intercept patients at very early stage.
Chiara Bellocchi, Shervin Assassi, Marka Lyons, Maurizio Marchini, Chandra Mohan, Alessandro Santaniello, Lorenzo Beretta   +6 more
doaj   +1 more source

Fibrosing arthropathy in juvenile scleroderma

Современная ревматология, 2021
The group of scleroderma diseases includes a number of clinical entities, the main symptom of which is skin tightening. Scleroderma is a prominent example of these diseases, characterized by excessive synthesis and deposition of collagen in organs and ...
D. A. Dibrov, M. N. Starovoitova, O. V. Desinova   +2 more
doaj   +1 more source

Localized scleroderma: clinical spectrum and therapeutic update [PDF]

Anais Brasileiros de Dermatologia, 2015
Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis ...
Mariana Figueiroa Careta, Ricardo Romiti
doaj   +2 more sources

Renal Involvement in Systemic Sclerosis: An Update

Kidney & Blood Pressure Research, 2020
Background: Systemic sclerosis is an immune-mediated rheumatic disease characterized by vascular abnormalities, tissue fibrosis and autoimmune phenomena.
Magdalena Chrabaszcz, Jolanta Małyszko, Mariusz Sikora, Rosanna Alda-Malicka, Anna Stochmal, Joanna Matuszkiewicz-Rowinska, Lidia Rudnicka   +6 more
doaj   +1 more source

Cultural adaptation and validation of the scleroderma health assessment questionnaire into Arabic language

Egyptian Rheumatology and Rehabilitation, 2023
Background Systemic sclerosis is an autoimmune multisystem disorder which affects the patients’ physical and psychological functioning. Scleroderma health assessment questionnaire used to measure physical disability in systemic sclerosis patients.
Samah Mahmoud Alian, Enass Abdel-kader Eliwa, Sohair Atia Ahmed, Manar Ibrahim Abd El-Fattah Ibrahim   +3 more
doaj   +1 more source

Preliminary safety and efficacy profile of prucalopride in the treatment of systemic sclerosis (SSc)-related intestinal involvement: results from the open label cross-over PROGASS study

Arthritis Research & Therapy, 2017
Background Prokinetics are used to treat enteric dismotility symptoms in systemic sclerosis (SSc) patients, but they often lack adequate efficacy. The most effective prokinetics belonging to the serotonin (5-HT4) receptor agonists class were withdrawn ...
Barbara Vigone, Monica Caronni, Adriana Severino, Chiara Bellocchi, Anna Rita Baldassarri, Mirella Fraquelli, Gaia Montanelli, Alessandro Santaniello, Lorenzo Beretta   +8 more
doaj   +1 more source

Sine scleroderma, limited cutaneous, and diffused cutaneous systemic sclerosis survival and predictors of mortality

Arthritis Research & Therapy, 2021
Highlights • Male sex, cardiac involvement, DLCO 5 mg/l are strong predictors of mortality in systemic sclerosis. • This study shows the survival of subtypes and in particular sine scleroderma. • Sine scleroderma subtype has better survival than diffuse
Sébastien De Almeida Chaves, Tiphaine Porel, Mickael Mounié, Laurent Alric, Léonardo Astudillo, Antoine Huart, Olivier Lairez, Martin Michaud, Grégoire Prévot, David Ribes, Laurent Sailler, Francis Gaches, Daniel Adoue, Gregory Pugnet   +13 more
doaj   +1 more source

Refractory scleroderma renal crisis precipitated after high-dose oral corticosteroids and concurrent intravitreal injection of bevacizumab

SAGE Open Medical Case Reports, 2020
Scleroderma renal crisis is a serious complication that can develop in certain patients with systemic sclerosis. Some risks have been identified as potential triggers of scleroderma renal crisis, including the high-dose oral corticosteroids.
Ramy M Hanna, Lama Abdelnour, Jonathan E Zuckerman, Antoney J Ferrey, Alex Pai, Kambiz Vahabzadeh, James Wilson, Everado A Torres, Kamyar Kalantar-Zadeh, Ira B Kurtz   +9 more
doaj   +1 more source

Scleroderma with Nodular Scleroderma

Case Reports in Dermatology, 2016
Background: Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea. A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type.
Chutika Srisuttiyakorn, Kobkul Aunhachoke   +1 more
doaj   +1 more source

Calcinosis circumscripta of the breasts: The deeper meaning

South African Journal of Radiology, 2023
Calcinosis circumscripta involving the breasts usually hints at an underlying systemic cause, most commonly connective tissue disorders such as scleroderma or dermatomyositis.
Tanusha Sewchuran, Joel M. Kabeya
doaj   +1 more source