Results 11 to 20 of about 893,246 (219)

Antiphospholipid Antibodies and Systemic Scleroderma

open access: yesTurkish Journal of Hematology, 2013
Objective: Antiphospholipid antibodies (APLs) could be associated with an increased risk of vascular pathologies in systemic scleroderma. The aim of our study was to search for APLs in patients affected by systemic scleroderma and to evaluate their ...
Awa Oumar Touré   +8 more
doaj   +2 more sources

Scleroderma with Nodular Scleroderma

open access: yesCase Reports in Dermatology, 2016
Background: Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea. A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type.
Chutika Srisuttiyakorn   +1 more
doaj   +2 more sources

Systemic Scleroderma in Childhood: A Case Report

open access: yesThe Turkish Journal of Gastroenterology, 2014
Juvenile systemic scleroderma is a rare chronic multi-system connective tissue disease in childhood. Although rare in children, it is an important cause of morbidity and mortality.
Aslı ASLAN   +3 more
doaj   +2 more sources

DIAGNOSTIC VALUE OF CERULOPLASMIN IN SYSTEMIC SCLERODERMA [PDF]

open access: yesМедицинская иммунология, 2019
Objective of study: refining immune diagnostics of systemic scleroderma through determining ceruloplasmin antibodies, its amount and enzymatic activity, as well as control of effectiveness of therapy with ceruloplasmin-based immobilized ...
O. I. Emelyanova   +3 more
doaj   +2 more sources

Modern Pathogenetic Mechanisms of Systemic Scleroderma [PDF]

open access: yes, 2023
Systemic scleroderma is a chronic and often progressive autoimmune inflammation of the connective tissue, characterized by fibrosis of the skin and internal organs, widespread vascular lesions with unknown etiology, and heterogeneous clinical ...
Botirbekov Abdurashid Nazarkulovich
core   +1 more source

Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group [PDF]

open access: yes, 2012
INTRODUCTION: Erectile dysfunction (ED) is common in men with systemic sclerosis (SSc) but the demographics, risk factors and treatment coverage for ED are not well known.
Smith, Vanessa   +62 more
core   +1 more source

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]

open access: yes, 2015
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Ayuko Takahashi (789901)   +35 more
core   +1 more source

Application and performance of disease activity indices proposed for patients with systemic sclerosis in an international cohort of patients with juvenile systemic sclerosis [PDF]

open access: yes, 2023
Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: the inception cohort project is supported by an unrestricted grant from the Joachim Herz Stiftung ...
Adrovic, Amra   +32 more
core   +1 more source

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients [PDF]

open access: yes, 2001
Patients with scleroderma receiving Iloprost as a treatment for severe Raynaud's phenomenon report a reduction in skin tightness, suggesting that this drug inhibits skin fibrosis.
Stratton, R   +17 more
core   +1 more source

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis [PDF]

open access: yes, 2013
Systemic sclerosis (SSc) is a fibrotic autoimmune disease in which the genetic component plays an important role. One of the strongest SSc association signals outside the human leukocyte antigen (HLA) region corresponds to interferon (IFN) regulatory ...
Schuerwegh, A. J.   +219 more
core   +2 more sources

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