Results 191 to 200 of about 41,669 (215)

Mortality in Systemic Sclerosis (Scleroderma)

QJM: An International Journal of Medicine, 1992
Two hundred and thirty-seven patients with systemic sclerosis were followed prospectively in a scleroderma clinic. The overall 3, 6, and 9-year survival rates were 86, 76 and 61 per cent respectively. Renal, cardiac and pulmonary disease, and older age at enrollment were adverse prognostic factors associated with reduced survival.
M Aubrey, I Khostanteen, Jan P. Dutz, C A Alderdice, P. Lee, P A Baer, P Langevitz, D Buskila, S Piper, M Baron   +9 more
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Progressive Systemic Sclerosis (Scleroderma)

Australasian Annals of Medicine, 1970
SummarySixteen cases of progressive systemic sclerosis (PSS) were studied in a large general hospital in Singapore from 1957 to 1967. Thirteen were Chinese and 3 Malays. The majority were middle‐aged housewives and half of the cases were seen less than six months after onset.
Oon Teik Khoo, Chong Hai Tay
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Vitiligolike Macules in Systemic Scleroderma

Archives of Dermatology, 1983
Changes of hyperpigmentation and depigmentation in systemic scleroderma have been known since the last century, but their relationship to the pathogenesis of the condition is poorly understood. Clinical, histologic, histochemical, immunopathologic, and electron microscopic studies of the depigmented lesions in seven patients with systemic scleroderma ...
Nestor P. Sanchez, Miguel Vázquez, Jorge L. Sánchez   +2 more
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Erosive Arthropathy in Systemic Scleroderma

JAMA: The Journal of the American Medical Association, 1975
ALTHOUGH the classic bony changes seen in systemic scleroderma may be accompanied by changes in the joints, only rarely is destruction of subchondral bone found in joint spaces. 1-3 However, roentgenograms of the hand of a 64-year-old woman with systemic scleroderma who was seen recently at the Lahey Clinic showed a classic pencil-in-cup (mortar and ...
William P. Beetham, Wayne Wild
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Systemic Scleroderma and Pregnancy

1999
Abstract Young women with systemic scleroderma often ask me if it is okay to get pregnant. The answer is that it depends on several factors: the stage of the disease, the medications that are required to control the disease, and the risks that people are willing to take in order to have a child.
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Epidemiology of Systemic Sclerosis (Scleroderma)

Annals of Internal Medicine, 1971
Abstract A large-scale epidemiologic study of scleroderma was completed, including 86 patients who met specified criteria and who were hospital-diagnosed from 1947 through 1968.
Thomas A. Medsger, Alfonse T. Masi
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The genetics of scleroderma (systemic sclerosis)

Current Opinion in Rheumatology, 2010
To determine the advances made in the genetics of scleroderma in candidate gene association studies.Over the past 18 months, a number of candidate gene studies using large case-control series in scleroderma have been reported. The studies have identified multiple genes involved in immune regulation including BANK1, C8orf13-BLK, IL-23R, IRF5, STAT4 ...
John D. Reveille, Sandeep K. Agarwal
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Systemic sclerosis (scleroderma)

1991
Estimating prognosis in systemic sclerosis is particularly difficult for a number of reasons. First, it is a disorder of remarkable clinical heterogeneity. Patients may be classified as having diffuse (widespread) or limited (restricted) cutaneous involvement. Additional variants not yet described are likely to exist.
Virginia D. Steen, Thomas A. Medsger
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Scleroderma (Systemic Sclerosis) [PDF]

, 2010
Scleroderma is a systemic disease characterized by progressive fibrosis of the skin and multiple organs. The term “scleroderma” means literally “hard skin”
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Systemic Sclerosis (Scleroderma)

Archives of Dermatology, 1986
This book is based on the proceedings of the International Conference on Scleroderma held in Austin, Tex in 1981. The coverage is encyclopedic, ranging from history to animal models, epidemiology to therapy. The individual chapters are in brief report format with useful references.
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