Results 71 to 80 of about 1,850,678 (233)

Prediction and forecasting models based on patient's history and biomarkers with application to Scleroderma disease [PDF]

open access: yesarXiv, 2018
This paper aims at predicting lung function values based on patients historical lung function values and serum biomarkers in Scleroderma patients. The progression of disease is measured by three lung function indexes (FVC, TLC, DLCO). Values of four biomarkers (TIMP1, P3NP, HA, NT-proBNP) are available.
arxiv  

Development of an immunoprecipitation assay for detecting anti‐3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase autoantibodies using a non‐radioactive biotinylated recombinant protein

open access: yesClinical and Experimental Neuroimmunology, EarlyView.
Principle and performance of an immunoprecipitation assay for detecting anti‐3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase (HMGCR) autoantibodies using a non‐radioactive biotinylated recombinant protein. This new assay can serve as a potential alternative to the gold standard immunoprecipitation assay for detecting anti‐anti‐3‐hydroxy‐3 ...
Yukihiro Nishikawa   +8 more
wiley   +1 more source

Disease Trajectory Maps [PDF]

open access: yesarXiv, 2016
Medical researchers are coming to appreciate that many diseases are in fact complex, heterogeneous syndromes composed of subpopulations that express different variants of a related complication. Time series data extracted from individual electronic health records (EHR) offer an exciting new way to study subtle differences in the way these diseases ...
arxiv  

Equivariant Filter Design for Kinematic Systems on Lie Groups [PDF]

open access: yesarXiv, 2020
It is known that invariance and equivariance properties for systems on Lie groups can be exploited in the design of high performance and robust observers and filters for real-world robotic systems. This paper proposes an analysis framework that allows any kinematic system on a Lie group to be embedded in a natural manner into an equivariant kinematic ...
arxiv  

The diagnosis and classification of scleroderma (systemic sclerosis).

open access: yesPostgraduate medical journal, 1988
Difficulty in the diagnosis of the disease scleroderma may occur at the early stage prior to the development of obvious skin sclerosis. A presumptive diagnosis may be made if Raynaud's phenomenon is accompanied by a positive 'neck test', 'scleroderma ...
Alfred J. Barnett   +2 more
semanticscholar   +1 more source

Adalimumab Monotherapy or Combination Therapy With Methotrexate in Paediatric Uveitis: Data From the AIDA Network Uveitis Registry

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and in combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Methods Registry‐based observational study. Children receiving ADA for active uveitis were divided into the ADA monotherapy group (group 1) and the ADA plus ...
Carla Gaggiano   +40 more
wiley   +1 more source

Estimating AutoAntibody Signatures to Detect Autoimmune Disease Patient Subsets [PDF]

open access: yesarXiv, 2017
Autoimmune diseases are characterized by highly specific immune responses against molecules in self-tissues. Different autoimmune diseases are characterized by distinct immune responses, making autoantibodies useful for diagnosis and prediction. In many diseases, the targets of autoantibodies are incompletely defined.
arxiv  

Dental Implant Therapy in Patients With Autoimmune Diseases: A Scoping Review

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The aim of this scoping review is to determine the effects of autoimmune diseases (ADs) and the agents used for treatment on dental implant survival and biologic outcomes. Material and Methods An electronic database search was performed in MEDLINE (PubMed), The Cochrane Library, and Embase on 29‐04‐2024.
Emil Hyldahl   +2 more
wiley   +1 more source

A Bayesian Approach to Restricted Latent Class Models for Scientifically-Structured Clustering of Multivariate Binary Outcomes [PDF]

open access: yesarXiv, 2018
In this paper, we propose a general framework for combining evidence of varying quality to estimate underlying binary latent variables in the presence of restrictions imposed to respect the scientific context. The resulting algorithms cluster the multivariate binary data in a manner partly guided by prior knowledge.
arxiv  

Orofacial Manifestations and Temporomandibular Disorders of Systemic Scleroderma: An Observational Study

open access: yesInternational Journal of Molecular Sciences, 2016
Scleroderma is a disorder involving oral and facial tissues, with skin hardening, thin lips, deep wrinkles, xerostomia, tongue rigidity, and microstomia. The aim of this study was to investigate the prevalence of oral manifestations and temporomandibular
V. Crincoli   +6 more
semanticscholar   +1 more source

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