Results 71 to 80 of about 41,669 (215)
DIAGNOSTIC VALUE OF CERULOPLASMIN IN SYSTEMIC SCLERODERMA
Objective of study: refining immune diagnostics of systemic scleroderma through determining ceruloplasmin antibodies, its amount and enzymatic activity, as well as control of effectiveness of therapy with ceruloplasmin-based immobilized ...
O. I. Emelyanova+3 more
doaj +1 more source
Introduction: Nail fold dermoscopy is a noninvasive technique which aids in the diagnosis of systemic sclerosis. It also helps in predicting the extent and stage of microvascular damage.
Priya Sara Kuryan+4 more
doaj +1 more source
Objective The transition from asymptomatic anti‐nuclear antibody (ANA) positivity to systemic autoimmune rheumatic disease (SARD) is associated with increased production of pro‐inflamamtory factors such as TNF‐α. Here we investigate whether the relative absence of inflammation in asymptomatic ANA+ individuals (ANA+NS) results from a lack of circulating
Carolina Muñoz‐Grajales+8 more
wiley +1 more source
Left ventricular mass and intrarenal arterial stiffness as early diagnostic markers in cardiorenal syndrome type 5 due to systemic sclerosis [PDF]
Background: Cardiorenal syndrome type 5 (CRS-5) includes a group of conditions characterized by a simultaneous involvement of the heart and kidney in the course of a systemic disease.
AMOROSO, Antonio+11 more
core +1 more source
B cells and systemic sclerosis interstitial lung disease
Interstitial lung disease is an important complication of systemic sclerosis (SSc‐ILD) with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to FDA‐approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of interstitial lung diseases of other systemic autoimmune ...
Nina Goldman+2 more
wiley +1 more source
Prognostic impact of coronary microcirculation abnormalities in systemic sclerosis: a prospective study to evaluate the role of non-invasive tests [PDF]
INTRODUCTION: Microcirculation dysfunction is a typical feature of systemic sclerosis (SSc) and represents the earliest abnormality of primary myocardial involvement.
CAULI, ALBERTO+9 more
core +1 more source
ACUTE RENAL FAILURE – REVEALING MANIFESTATION OF AN AUTOIMMUNE CONDITION [PDF]
Scleroderma renal crisis is an important cause of morbidity and mortality in systemic sclerosis patients, occurring in about 5-10% of the cases. It is seen mostly early in the progression of the disease, about 75% of the scleroderma renal crises ...
Iulia Andronache+4 more
doaj +1 more source
Laboratory Practices for the Detection and Characterization of Cryoglobulins and Cryofibrinogen
This study shows the importance of carrying out the search for both cryoproteins, cryoglobulins, and cryofibrinogen in cases of strong clinical suspicion of cryoproteinemia, despite their complex but not impossible detection. Use of correct procedures from the pre‐preanalytical phase up to reporting, of alternative methods such as immunotyping and the ...
Teresa Troiano+5 more
wiley +1 more source
The final systemic sclerosis patients with interstitial lung disease (SSc‐ILD) progression prediction model was composed of 6 significant risk factors: male, type 2 diabetes mellitus, pericardial effusion, anti‐Ro52, hypoproteinemia, and elevated C‐reactive protein. Our model demonstrated excellent prognostic utility.
Xi Cao+6 more
wiley +1 more source
A rare cutaneous manifestation of systemic sclerosis
A 43-year-old male with a history of intravenous drug use and alcohol consumption presented to the emergency department with three-month history of failure to thrive.
Joelle Sleiman+3 more
doaj +1 more source