Results 81 to 90 of about 734,275 (243)

Systemic lupus erythematosus‐associated autoantibodies in sickle cell disease: Spontaneous emergence in a patient and in transgenic sickle mice

British Journal of Haematology, Volume 206, Issue 4, Page 1213-1217, April 2025.
Summary We describe a patient with sickle cell disease (SCD) and elevated antiphospholipid antibodies (aPL) who developed multi‐organ failure resembling catastrophic antiphospholipid syndrome. Autoimmune screening revealed several autoantibodies characteristic of systemic lupus erythematosus (SLE). Notably, routinely housed and unmanipulated transgenic
Urshita Sinha, Suman Setty, Céleste Pilon, Julia J. Brown, Maria Armila Ruiz, Guohui Ren, Joyce Rauch, Santosh L. Saraf, Jerrold S. Levine   +8 more
wiley   +1 more source

Adalimumab Monotherapy or Combination Therapy With Methotrexate in Paediatric Uveitis: Data From the AIDA Network Uveitis Registry

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and in combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Methods Registry‐based observational study. Children receiving ADA for active uveitis were divided into the ADA monotherapy group (group 1) and the ADA plus ...
Carla Gaggiano, Alejandra de‐la‐Torre, Silvana Guerriero, Stefania Costi, Gaafar Ragab, Maria Pia Paroli, Emanuela Del Giudice, Luciana Breda, Saverio La Bella, Marco Cattalini, Maria Cristina Maggio, Alex Fonollosa, Ester Carreño, Maria Tarsia, Rosanna Dammacco, Soad Hashad, Antonio Vitale, Lampros Fotis, Stefano Gentileschi, Francesca Minoia, Germán Mejía‐Salgado, Halah Etayari, Paola Saboya‐Galindo, María Andrea Bernal‐Valencia, Adele Civino, Maria Sole Chimenti, Valeria Caggiano, Maria Francesca Gicchino, Jurgen Sota, Angela Mauro, Giuseppe Lopalco, Kalpana Babu Murthy, Mohamed Tharwat Hegazy, Vishali Gupta, Francesco La Torre, Rana Hussein Amin, Bruno Frediani, Gian Marco Tosi, Luca Cantarini, Claudia Fabiani, on behalf of the AIDA Network   +40 more
wiley   +1 more source

Prediction and forecasting models based on patient's history and biomarkers with application to Scleroderma disease [PDF]

arXiv, 2018
This paper aims at predicting lung function values based on patients historical lung function values and serum biomarkers in Scleroderma patients. The progression of disease is measured by three lung function indexes (FVC, TLC, DLCO). Values of four biomarkers (TIMP1, P3NP, HA, NT-proBNP) are available.
arxiv  

Role of cellular senescence and NOX4-mediated oxidative stress in systemic sclerosis pathogenesis. [PDF]

, 2015
Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by progressive fibrosis of skin and numerous internal organs and a severe fibroproliferative vasculopathy resulting frequently in severe disability and high mortality.
A Diazdeleon, A Dooley, A Erol, A Freund, A Gabrielli, A Gabrielli, A Gabrielli, A MacIntyre, A Salminen, A Servettaz, A Siani, A Sturrock, A Volpe, A Volpe, A Yoshizaki, AN Lyle, AZ Debbi, B Eckes, B Laleu, CB Harley, CD Bondi, CM Arlett, CM Stein, D Gvaramia, D Muñoz-Espin, D Muñoz-Espin, D Volonte, DE Furst, DF Murrell, E Rosato, E Savas, E Sikora, E Tourkina, E Tufvesson, ER Jarman, F Boin, F Gaggini, F Galdo Del, F Galdo Del, F Jiang, F Ogawa, F Ogawa, F Ogawa, F Tarhan, G Bai, G Simonini, GL Erre, GL Erre, H Sumimoto, H Xia, I Ben-Porath, I Cucoranu, I Montorfano, J Avouac, J Campisi, J El-Benna, J Goronzy, J Varga, JA Kim, JD Lambeth, JD Morrow, JF Passos, JF Passos, JH Chen, JL Barnes, JL Cracowski, JL Cracowski, JM Deursen van, JP Coppe, K Bedard, K Shimizu, KM Holmström, L Hayflick, L Hayflick, L Hecker, L Hecker, L Serrander, LL Song, M Böhm, M Chilosi, M Collado, M Elhai, M Geiszt, M Matucci-Cerinic, M Muller, M Schieber, M Storer, MD Mayes, MP Steele, MY Armanios, N Amara, N Duerrschmidt, N Manickam, N Sampson, O Babalola, P Cipriani, P Sambo, P Sambo, P Sambo, P Shivshankar, PS Tsou, Q Chen, QM Chen, R Salama, S Altenhöfer, S Bhattacharyya, S Parrinello, S Svegliati, Sergio A. Jimenez, SJ An, SK Parapuram, Sonsoles Piera-Velazquez, SR Datla, T Aoyama, T Finkel, T Kawahara, T Kuilman, T Ohtsuka, T Tchkonia, TK Kim, TR Katsumoto, VG Gorgoulis, VI Dumit, VJ Thannickal, WK Marut, WL Shen, X Duan, XM Wang, Y Allanore, Y Allanore, YH Paik   +130 more
core   +2 more sources

Dental Implant Therapy in Patients With Autoimmune Diseases: A Scoping Review

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The aim of this scoping review is to determine the effects of autoimmune diseases (ADs) and the agents used for treatment on dental implant survival and biologic outcomes. Material and Methods An electronic database search was performed in MEDLINE (PubMed), The Cochrane Library, and Embase on 29‐04‐2024.
Emil Hyldahl, Henning Schliephake, Simon Storgård Jensen   +2 more
wiley   +1 more source

Disease Trajectory Maps [PDF]

arXiv, 2016
Medical researchers are coming to appreciate that many diseases are in fact complex, heterogeneous syndromes composed of subpopulations that express different variants of a related complication. Time series data extracted from individual electronic health records (EHR) offer an exciting new way to study subtle differences in the way these diseases ...
arxiv  

Equivariant Filter Design for Kinematic Systems on Lie Groups [PDF]

arXiv, 2020
It is known that invariance and equivariance properties for systems on Lie groups can be exploited in the design of high performance and robust observers and filters for real-world robotic systems. This paper proposes an analysis framework that allows any kinematic system on a Lie group to be embedded in a natural manner into an equivariant kinematic ...
arxiv  

Evaluation of estimated glomerular filtration rate and clinical variables in systemic sclerosis patients [PDF]

, 2016
Objectives: The most important renal complication of systemic sclerosis (SSc) is scleroderma renal crisis (SRC). Many patients demonstrate less severe renal complications, most likely associated with reduced renal blood flow and a consequent reduction in
Amoroso, Antonio, Barbano, Biagio, Cianci, Rosario, Gigante, Antonietta, Granata, Guido, Quarta, Silvia, Rosato, Edoardo, Salsano, Felice   +7 more
core   +1 more source

Circulating Fetuin‐A concentrations in rheumatic diseases: a systematic review and meta‐analysis

European Journal of Clinical Investigation, Volume 55, Issue 5, May 2025.
In this systematic review with meta‐analysis, we identified 19 eligible studies to determine whether there is any change in Fetuin‐A (FtA) concentrations in patients with rheumatic diseases. We observed a significant decrease in FtA concentrations in RD patients (standardized mean difference, SMD = −.91; 95% CI −1.43 to −.39, p = .001).
Biagio Di Lorenzo, Stefano Zoroddu, Arduino A. Mangoni, Panagiotis Paliogiannis, Gian Luca Erre, Ciriaco Carru, Angelo Zinellu   +6 more
wiley   +1 more source

A rare cutaneous manifestation of systemic sclerosis

European Journal of Case Reports in Internal Medicine
A 43-year-old male with a history of intravenous drug use and alcohol consumption presented to the emergency department with three-month history of failure to thrive.
Joelle Sleiman, Taimur Aslam, Anastasia Slobodnick, Alina G. Bridges   +3 more
doaj   +1 more source