Localized scleroderma – classification and tools used for the evaluation of tissue damage and disease activity/severity [PDF]
, 2017 Localized scleroderma is a rare autoimmune disorder affecting the dermis, subcutaneous tissue and deeper structures. The course of localized scleroderma includes three stages: early inflammation, progressive sclerosis and atrophy. The active stage of the
Dorota Krasowska +1 more
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Expert Perspectives: Defining and managing progressive pulmonary fibrosis in systemic sclerosis
Arthritis &Rheumatology, Accepted Article.‐‐
Devis Benfaremo +7 more
wiley +1 more source
Dental care in scleroderma – What should we know about scleroderma?
, 2019 Scleroderma is a disease of the connective tissue that is characterized by autoimmune reactions, excess collagen deposition and vascular hyperactivity and phenomena. It can affect virtually anyone at any age although having a predisposition towards women
Theos, Papaefstathiou
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Defining genetic risk factors for scleroderma-associated interstitial lung disease : IRF5 and STAT4 gene variants are associated with scleroderma while STAT4 is protective against scleroderma-associated interstitial lung disease [PDF]
, 2019 Although several genetic associations with scleroderma (SSc) are defined, very little is known on genetic susceptibility to SSc-associated interstitial lung disease (SSc-ILD).
Maher, Toby M +35 more
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Association of Childhood Acute Leukemia With Autoimmune Diseases
International Journal of Cancer, EarlyView.A possible link exists between various pediatric autoimmune diseases (AIDs) and increased risk of childhood leukemia. Although immune dysregulation is a key feature of these conditions, the connection between them remains unclear. In this study, using cancer registry data in Finland, the authors examined associations between AIDs and childhood acute ...
Ida Pellikka +4 more
wiley +1 more source
Rosiglitazone alleviates the persistent fibrotic phenotype of lesional skin scleroderma fibroblasts
, 2010 Objective - The transcription factor peroxisome proliferator-activated receptor (PPAR)-γ plays an important role in controlling cell differentiation. The aim of the present study was to examine whether PPAR-γ expression was reduced in skin scleroderma ...
Stratton, R.J. +5 more
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Characterization of Pulmonary Functional Abnormalities in Systemic Sclerosis Using Xenon MRI
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Xenon MRI is increasingly used to evaluate patients with interstitial lung disease (ILD) and pulmonary hypertension (PH), both of which are common manifestations of systemic sclerosis (SSc). As such, Xe‐MRI may be suited to interrogate lung function impairment in SSc.
Dawson Shaver +11 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Scleromyxedema (SMX) is a cutaneous mucinosis characterised by an abnormal accumulation of mucin in the skin and limited treatment options. Assessment of therapy response during treatment is challenging. Objectives Patients with SMX receiving high‐dose intravenous IVIg therapy were included to assess validity of the double modified ...
Julia K. Winkler, Alexander H. Enk
wiley +1 more source
Optimization of Scleroderma spore inoculum for Eucalyptus nurseries in China
, 2006 Scleroderma, a genus of ectomycorrhizal (ECM) fungi, is often associated with trees in disturbed habitats and is therefore considered to be suitable for use in plantation forestry.
Chen, Yinglong
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Evaluating the cutaneous involvement in scleroderma : Torsional stiffness revisited
, 2001 Objective: The pace, progression and extent of the skin lesions in scleroderma may parallel the risk of new internal organ involvement and the progression of existing internal lesions.
Helliwell, Phillip S. +3 more
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