Results 101 to 110 of about 2,393 (163)

Development and Validation of the Brief Support Group Leader Self‐Efficacy Scale Among Scleroderma Peer Support Group Leaders

open access: yesACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective Our objective was to develop a brief Support Group Leader Self‐efficacy Scale (Brief‐SGLSS) that maintains the core content and measurement properties of the full 32‐item SGLSS among systemic sclerosis (SSc) support group leaders. Methods Development and validation involved four steps conducted by researchers and a Support Group Advisory Team
Sabrina Provencher   +16 more
wiley   +1 more source

Prevalence and Risk Factors for Esophageal Strictures in Systemic Sclerosis

open access: yesACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective Gastroesophageal reflux disease (GERD) affects up to 90% of patients with systemic sclerosis (SSc). Chronic esophageal acid exposure can result in complications including the formation of esophageal strictures (ES). Proton pump inhibitors can alter gastric acid pH and improve GORD symptoms; however, there have been no recent studies ...
Alannah Quinlivan   +13 more
wiley   +1 more source

Scleroderma [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1908
openaire   +2 more sources

Clinical Associations of Anti‐RNPC3 Autoantibodies in Mixed Connective Tissue Disease

open access: yesACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective The RNA‐binding region‐containing protein 3 (RNPC3) protein acts as a molecular bridge, promoting U11/U12 RNP complex formation. In previous reports, patients with systemic sclerosis (SSc) with anti‐RNPC3 autoantibodies had an increased risk of interstitial lung disease (ILD), severe gastrointestinal (GI) disease, and cancer.
Darya S. Jalaledin   +14 more
wiley   +1 more source

Romosozumab‐Associated Recurrent Erythema Nodosum in Mixed Connective Tissue Disease

open access: yesACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective The aim of this study was to describe recurrent erythema nodosum (EN) temporally associated with romosozumab in a patient with mixed connective tissue disease and to examine the biologic plausibility of this association in the context of Wnt/β‐catenin–mediated immune regulation.
Jose Luis Diaz Macip   +5 more
wiley   +1 more source

Distinct Effects of Complement C4A and C4B Copy Numbers in Systemic Sclerosis Serological and Clinical Subtypes

open access: yesArthritis &Rheumatology, Volume 78, Issue 4, Page 904-913, April 2026.
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. The variable copy number (CN) of C4 genes and retroviral human endogenous retrovirus K (HERV‐K) element influence its function.
Javier Martínez‐López   +156 more
wiley   +1 more source

Drug‐Induced Raynaud's Phenomenon and Underlying Mechanism: A Disproportionality Analysis From the World Health Organization Pharmacovigilance Database

open access: yesArthritis &Rheumatology, Volume 78, Issue 4, Page 985-992, April 2026.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty   +4 more
wiley   +1 more source

Pellagra From Tryptophan Depletion in Carcinoid Syndrome due to a Pulmonary Atypical Carcinoid Neuroendocrine Tumor

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Pellagra may complicate functioning pulmonary atypical carcinoid and present as a subtle acral dermatosis rather than the classical photo‐distributed rash. In neuroendocrine tumor patients with chronic diarrhea and new skin changes, clinicians should suspect niacin deficiency and consider empiric nicotinamide, even when niacin assays are ...
Ahmar Iftikhar Talib   +2 more
wiley   +1 more source

A Complex Inflammatory Triad: A Rare Case of Parry‐Romberg Syndrome With Systemic Lupus Erythematosus and Thyroiditis

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Parry‐Romberg Syndrome (PRS) is a rare disorder characterized by progressive unilateral facial atrophy, traditionally viewed as a localized scleroderma variant. Its rare coexistence with systemic lupus erythematosus (SLE) and autoimmune thyroiditis (AIT) suggests a broader inflammatory etiology, challenging the notion of PRS as a purely ...
Sakib Abrar   +4 more
wiley   +1 more source

Intestinal Lipoma as a Cause of Sigmoid Colo‐Colic Intussusception in an Adult: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Adult intussusception is an uncommon and often unexpected diagnosis, typically driven by an underlying structural lesion. We report the case of a 43‐year‐old woman who presented with a month‐long constipation, five days of worsening intermittent abdominal pain associated with nausea, bilious vomiting, and anorexia.
Shankar Adhikari   +2 more
wiley   +1 more source

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