Results 101 to 110 of about 80,483 (293)

Gastrointestinal symptoms and motility disorders in patients with systemic scleroderma

open access: yesBMC Gastroenterology, 2008
Background Studies on gastrointestinal symptoms, dysfunctions, and neurological disorders in systemic scleroderma are lacking so far. Methods Thirty-eight scleroderma patients (34 limited, 4 diffuse), 60 healthy controls and 68 dyspeptic controls were ...
Palasciano Giuseppe   +6 more
doaj   +1 more source

Eosinophilic fasciitis (Shulman's disease): review and comparative evaluation of seven patients. [PDF]

open access: yes, 2019
OBJECTIVES: Eosinophilic fasciitis (EF) was described in 1974 by Shulman as a rare fibrosing connective tissue disease of unknown etiology. An undetermined trigger is thought to lead to the degranulation of eosinophils that interact with fibroblasts and
Cimbron, M   +3 more
core   +1 more source

Multi‐omic analysis identifies biological processes underlying progressive interstitial lung disease in systemic sclerosis

open access: yesThe FEBS Journal, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease, and lung complications (ILD) are the main cause of death. This study compared SSc patients with and without lung disease to healthy volunteers. We found increased inflammation, specific proteins, and higher triglyceride levels linked to lung disease progression. These findings suggest triglycerides
Selena Bouffette   +16 more
wiley   +1 more source

Anti‐Ro52/TRIM21 autoantibodies predict Sjögren's syndrome in patients with primary biliary cholangitis

open access: yesHepatology Research, EarlyView.
Abstract Background and aims Sjögren's syndrome is a common comorbidity in patients with primary biliary cholangitis (PBC). Anti‐Ro52 autoantibodies against the protein TRIM21 are often seen in Sjögren's syndrome. TRIM21 consists of four domains (PRY/SPRY, Coiled‐Coil, B‐box, and RING domain), each with a specific function.
Marie Louise Næstholt Dahl   +10 more
wiley   +1 more source

The Potential Role of Butyrate in the Pathogenesis and Treatment of Autoimmune Rheumatic Diseases

open access: yesBiomedicines
The gut microbiota is a complex ecosystem of microorganisms residing in the human gastrointestinal tract, playing a crucial role in various biological processes and overall health maintenance.
Carmela Coccia   +13 more
doaj   +1 more source

Sketching T cell atlases in the single‐cell era: challenges and recommendations

open access: yesImmunology &Cell Biology, EarlyView.
Recent advances in single‐cell technologies have enabled the creation of T cell atlases, providing detailed maps of adaptive immunity across tissues, development and disease states. These atlases help uncover T cell diversity, functional states and disease mechanisms, aiding in the identification of therapeutic targets.
Itana Bojović   +3 more
wiley   +1 more source

Challenges in management of a patient with oropharyngeal carcinoma and scleroderma

open access: yesOtolaryngology Case Reports, 2020
Objective: To discuss some of the challenges that can arise in the treatment of patients with oropharyngeal carcinoma and scleroderma, by presenting an illustrative case.
Nicole C. Schmitt   +5 more
doaj  

The Pathogenesis of Scleroderma

open access: yesIndian Journal of Rheumatology, 2017
Systemic sclerosis (SSc) results from the complex interplay between the immune system, vasculature and tissue-repair mechanisms. Endothelial injury is the prime event; environmental triggers in the susceptible individual trigger the pathologic process, which translates into fibrosis.
Gupta, L., Ahmed, S., Zanwar, A.
openaire   +4 more sources

Home - About - Disclaimer - Privacy