Results 161 to 170 of about 61,964 (279)
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz +3 more
wiley +1 more source
IL-17 Signaling Inhibitors in Localized Scleroderma: A Single-Center Case Series of Nine Patients. [PDF]
Takahashi T +5 more
europepmc +1 more source
Multiorgan fibrosis arises when chronic injury activates fibroblasts and remodels extracellular matrix, whose increasing stiffness sustains disease through mechanotransduction pathways. Bidirectional cellular‐matrix feedback operates across lung, heart, liver, and kidney.
Amedeo Lonardo, Ralf Weiskirchen
wiley +1 more source
Nodular Scleroderma in a Patient With Anti-RNA Polymerase III-Antibody Positive Systemic Sclerosis: A Case Report and Literature Review. [PDF]
Kanno K, Kobayashi Y, Fujita Y.
europepmc +1 more source
Pharmacological mechanisms and physiologic effects of GLP‐1 receptor agonists relevant to peri‐endoscopic risk. ABSTRACT The global increase in obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD) has led to a higher use of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) among patients ...
Junaid Beig +7 more
wiley +1 more source
Nailfold Videocapillaroscopy in Pediatric Rheumatology: Established Roles, Emerging Applications, and Future Perspectives. [PDF]
Öztürk K +4 more
europepmc +1 more source
Nailfold capillaroscopy is a non‐invasive imaging tool that can aid in the diagnosis and monitoring of juvenile myositis. Branched nailfold capillary morphology is more common in juvenile myositis patients, particularly those positive for TIF1γ+ autoantibodies. Juvenile myositis patients with more active disease demonstrate increased microhaemorrhages,
Nicholas McClellan +7 more
wiley +1 more source
Association of Childhood Acute Leukemia With Autoimmune Diseases
A possible link exists between various pediatric autoimmune diseases (AIDs) and increased risk of childhood leukemia. Although immune dysregulation is a key feature of these conditions, the connection between them remains unclear. In this study, using cancer registry data in Finland, the authors examined associations between AIDs and childhood acute ...
Ida Pellikka +4 more
wiley +1 more source
Safety and Microvascular Effect of Four-Year Aminaphtone Administration in Systemic Sclerosis Patients. [PDF]
Campitiello R +6 more
europepmc +1 more source

