Results 171 to 180 of about 61,964 (279)

Characterization of Pulmonary Functional Abnormalities in Systemic Sclerosis Using Xenon MRI

Journal of Magnetic Resonance Imaging, Volume 64, Issue 3, Page 655-666, September 2026.
ABSTRACT Background Xenon MRI is increasingly used to evaluate patients with interstitial lung disease (ILD) and pulmonary hypertension (PH), both of which are common manifestations of systemic sclerosis (SSc). As such, Xe‐MRI may be suited to interrogate lung function impairment in SSc.
Dawson Shaver, Steven Haworth, Evan Graumann, Bradie Frizzell, David H. Lee, Jiwoong Choi, Chase S. Hall, Scott M. Matson, Mark Hamblin, Mario Castro, Paul S. Schmidt, Peter J. Niedbalski   +11 more
wiley   +1 more source

High levels of vascular cell adhesion molecule-1 associate with a 'vasculopathic' phenotype in systemic sclerosis with higher mortality. [PDF]

Rheumatology (Oxford)
Parker MJS, Nikpour M, Hansen D, Hanson AL, Sahhar J, Brown MA, Corte TJ, Proudman S, Kenna TJ, Australian Scleroderma Interest Group.   +9 more
europepmc   +1 more source

Assessment of Treatment Response in Patients With Scleromyxedema by the Double Modified Rodnan Skin Score

JEADV Clinical Practice, Volume 5, Issue 3, Page 917-921, September 2026.
ABSTRACT Background Scleromyxedema (SMX) is a cutaneous mucinosis characterised by an abnormal accumulation of mucin in the skin and limited treatment options. Assessment of therapy response during treatment is challenging. Objectives Patients with SMX receiving high‐dose intravenous IVIg therapy were included to assess validity of the double modified ...
Julia K. Winkler, Alexander H. Enk
wiley   +1 more source

A Hospitalized Patient With Systemic Scleroderma Requiring ICU-Level Care. [PDF]

Cureus
Ghahary D, Goldstein B, Hong L, Maffey M.   +3 more
europepmc   +1 more source

Radiomic analysis of high-resolution computed tomography predicts interstitial lung disease progression and mortality in systemic sclerosis. [PDF]

Rheumatology (Oxford)
Iacovantuono M, Landini N, Jungblut L, Sauer GM, Käs F, Dobrota R, Muraru S, Elhai M, Mihai C, Becker MO, Chimenti MS, Frauenfelder T, Hoffmann-Vold AM, Distler O, Bruni C.   +14 more
europepmc   +1 more source

Ventilation Imaging of the Lung at 0.55T With Continuous Slice Cycling

Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1235-1244, September 2026.
ABSTRACT Purpose To propose and evaluate a novel method for pulmonary ventilation imaging, offering considerably improved SNR. Methods A continuous slice cycling (CSC) acquisition scheme is proposed to exclusively capture signal modulations from respiratory motion with increased SNR.
Andrea Leuthard, Grzegorz Bauman, Katrin E. Hostettler, Maurice Pradella, Oliver Bieri   +4 more
wiley   +1 more source

Integrative analysis of FAERS, network toxicology, and Mendelian randomization identifies potential targets in paclitaxel-associated systemic sclerosis. [PDF]

Front Immunol
Wang X, Zhang C.
europepmc   +1 more source

Lipodystrophy and adipose tissue recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis

The Journal of Pathology, Volume 270, Issue 1, Page 98-113, September 2026.
Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan, Piper Moore, Rohan Varshney, Miles Montegut, Qiannan Ma, Kayla Klatt, Reshmi Parameswaran, Elif G Ertugral, Chandrasekhar R Kothapalli, Michael C Rudolph, Radhika P Atit   +10 more
wiley   +1 more source

Rocky Paths: Family and Society as a Double-Edged Sword in the Strategies of Patients in Coping with Scleroderma: A Qualitative Descriptive Study. [PDF]

Iran J Nurs Midwifery Res
Mamashli L, Jahani S, Asadizaker M, Elahi N, Sayadi N, Rajaei E.   +5 more
europepmc   +1 more source

In Vivo Base Editing Partially Rescues Bone Dysplasia in a Mouse Model of Hutchinson‐Gilford Progeria Syndrome

Aging Cell, Volume 25, Issue 9, September 2026.
Hutchinson‐Gilford progeria syndrome (HGPS) is a premature aging disorder caused by a mutation in LMNA that produces the toxic progerin protein. In this study, an adenine base editor delivered via AAV9 achieved partial gene correction in HGPS mice when given at two weeks of age, partially rescuing bone structural and gene expression parameters and ...
Wayne A. Cabral, Caleb M. Grenko, Diana Yeritsyan, Indeevar Beeram, Shubham Laiwala, Lukas R. Johnson, Urraca L. Tavarez, Tingfen Yan, Stephen M. Wincovitch, Luke W. Koblan, Xin D. Gao, Meirui An, Narisu Narisu, Leslie G. Biesecker, David R. Liu, Ara Nazarian, Francis S. Collins, Michael R. Erdos   +17 more
wiley   +1 more source