Results 81 to 90 of about 56,983 (273)
arXiv, 2016 Medical researchers are coming to appreciate that many diseases are in fact complex, heterogeneous syndromes composed of subpopulations that express different variants of a related complication. Time series data extracted from individual electronic health records (EHR) offer an exciting new way to study subtle differences in the way these diseases ...
arxiv
The Mighty Fibroblast and Its Utility in Scleroderma Research
Journal of Scleroderma and Related Disorders, 2017 Fibroblasts are the effector cells of fibrosis characteristic of systemic sclerosis (SSc, scleroderma) and other fibrosing conditions. The excess production of extracellular matrix (ECM) proteins is the hallmark of fibrosis in different organs, such as ...
S. Garrett +2 more
semanticscholar +1 more source
JEADV Clinical Practice, EarlyView.Abstract Background Adjuvant immunotherapy (AIO) improved recurrence‐free survival (RFS) in patients with resected stages III–IV melanoma. Real‐world data, especially in elderly patients, as well as optimal management of patients who relpases, are still limited.
Manon Blaise +10 more
wiley +1 more source
A Framework for Individualizing Predictions of Disease Trajectories by Exploiting Multi-Resolution Structure [PDF]
arXiv, 2016 For many complex diseases, there is a wide variety of ways in which an individual can manifest the disease. The challenge of personalized medicine is to develop tools that can accurately predict the trajectory of an individual's disease, which can in turn enable clinicians to optimize treatments.
arxiv
Systematic autoantigen analysis identifies a distinct subtype of scleroderma with coincident cancer
Proceedings of the National Academy of Sciences of the United States of America, 2016 Significance In this study, we created a barcoded whole-genome ORF mRNA display library and combined it with phage-immunoprecipitation sequencing to look for autoantibodies in sera from patients with scleroderma who also had coincident cancer without a ...
G. Xu +6 more
semanticscholar +1 more source
The Interconnected World of Dermatology and Ophthalmology
JEADV Clinical Practice, EarlyView.ABSTRACT Medicine is a dynamic field that constantly discovers new links between different specialties. Dermatology and Ophthalmology are two related branches of medicine, having many similarities and interactions. The skin and the eyes both encounter various environmental challenges, such as ultraviolet radiation, allergens, infections, and trauma ...
Gyanesh Rathore +4 more
wiley +1 more source
Cell Transplantation, 2017 Mesenchymal stromal cells (MSCs) have received attention as an ideal source of regenerative cells because of their multipotent differentiation potential. Adipose tissue is an attractive source of MSCs.
Chiara Capelli +11 more
doaj +1 more source
Estimating AutoAntibody Signatures to Detect Autoimmune Disease Patient Subsets [PDF]
arXiv, 2017 Autoimmune diseases are characterized by highly specific immune responses against molecules in self-tissues. Different autoimmune diseases are characterized by distinct immune responses, making autoantibodies useful for diagnosis and prediction. In many diseases, the targets of autoantibodies are incompletely defined.
arxiv
Scientific Reports, 2016 Scleroderma is a group of rare diseases associated with early and transient inflammation and vascular injury, followed by fibrosis affecting the skin and multiple internal organs.
C. Del Río +11 more
semanticscholar +1 more source