Results 101 to 110 of about 11,032 (258)
Systemic Sclerosis Presenting with Simultaneous Retinal Vasculitis in One Eye and Optic Neuritis in the other along with Severe Immune Haemolytic Anaemia [PDF]
Journal of Clinical and Diagnostic Research, 2013 Systemic Sclerosis (SSc) is a connective tissue disorder which involves multiple systems in a chronic progressive manner. Micro–angiopathic haemolytic anaemia is a distinguished feature of “scleroderma renal crisis”, which is manifested by severe ...
Avijit Moulick +4 more
doaj +1 more source
A case report of malignant hypertension in a young woman [PDF]
, 2016 8noMalignant hypertension is a condition characterized by severe hypertension and multi-organ ischemic complications. Albeit mortality and renal survival have improved with antihypertensive therapy, progression to end-stage renal disease remains a ...
Bardelli, Moreno +7 more
core +2 more sources
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The FEBS Journal, EarlyView.The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Scleroderma Renal Crisis: A Pathology Perspective [PDF]
International Journal of Rheumatology, 2010 Scleroderma renal crisis (SRC) is an infrequent but serious complication of systemic sclerosis (SSc). It is associated with increased vascular permeability, activation of coagulation cascade, and renin secretion, which may lead to the acute renal failure typically associated with accelerated hypertension.
Batal, Ibrahim +3 more
openaire +2 more sources
Immunology, EarlyView.A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley +1 more source
, 2012 Scleroderma renal crisis (SRC) is an infrequent complication of a rare disease. To date, many aspects of the pathophysiology of SRC are still mysterious. Since SRC biopsies are not frequently encountered in practice, our understanding of the spectrum of histologic changes is derived from a combination of a limited personal experience and data obtained ...
Chabtini, Lola +6 more
openaire +3 more sources
Autoantibodies in systemic sclerosis: unanswered questions [PDF]
, 2015 Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular abnormalities, and cutaneous and visceral fibrosis. Serum autoantibodies directed to multiple intracellular antigens are present in more than 95% of patients and are considered a
Fritzler, Marvin J., Kayser, Cristiane
core +2 more sources
Photochemistry and Photobiology, EarlyView.Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde +6 more
wiley +1 more source
ACR Open Rheumatology, Volume 8, Issue 1, January 2026.Objective Systemic sclerosis (SSc) is known to exhibit significant epidemiologic and clinical variation. This study aimed to describe the clinical and epidemiologic characteristics of SSc in Alaska Native and American Indian (AN/AI) individuals in Alaska.
Vivek R. Mehta +5 more
wiley +1 more source
Case Reports in Nephrology, 2018 We had the challenged to treat a 40-year-old female with Systemic Scleroderma who was showing unspecific symptoms. During her time at the hospital she rapidly develops renal dysfunction, associated with hypertension.
Maite Hurtado Uriarte +2 more
doaj +1 more source