Profile of systemic sclerosis and associated renal involvement
Background: Systemic sclerosis (SSc) patients are encountered in all parts of the world. Few Indian studies are found in the literature on this connective tissue disorder of unknown etiology.
Neehar Shanavas, Anup K Das
doaj +1 more source
Systemic sclerosis associated interstitial lung disease - individualized immunosuppressive therapy and course of lung function: results of the EUSTAR group [PDF]
BACKGROUND: Interstitial lung disease in systemic sclerosis (SSc-ILD) is a major cause of SSc-related death. Imunosuppressive treatment (IS) is used in patients with SSc for various organ manifestations mainly to ameliorate progression of SSc-ILD.
Christopher P. Denton +16 more
core +5 more sources
A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa +7 more
wiley +1 more source
The association of low complement with disease activity in systemic sclerosis: a prospective cohort study [PDF]
Background: In some rheumatic diseases such as systemic lupus erythematosus (SLE), low serum complement ('hypocomplementaemia') is a feature of active disease. However, the role of hypocomplementaemia in systemic sclerosis (SSc) is unknown.
Brown, Z. +9 more
core +2 more sources
Renal pathology and clinical associations in systemic sclerosis: a historical cohort study
Pantipa Tonsawan,1 Komkid Talabthong,1 Anucha Puapairoj,2 Chingching Foocharoen11Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen ...
Tonsawan P +3 more
doaj
CURRENT VIEWS ON THE HETEROGENEITY OF RENAL INVOLVEMENTS IN PATIENTS WITH SYSTEMIC SCLEROSIS
Systemic sclerosis (SS), is an autoimmune connective tissue disease, the main clinical signs of which are due to disseminated microcirculatory disorders and fibrosis of the skin and viscera.
A. V. Gordeev +3 more
doaj +1 more source
Introduction: Systemic sclerosis is a chronic autoimmune disease, characterized by the triad of small vessel vasculopathy, immune system activation and increased deposits of extracellular matrix in the skin and internal organs.
Álvarez-Barreneche, María Fernanda +2 more
doaj +1 more source
Mixed connective tissue disease — enigma variations? [PDF]
In 1972, Sharp and colleagues described a new autoimmune rheumatic disease which they called mixed connective tissue disease (MCTD), characterized by overlapping features of systemic sclerosis (SSc), systemic lupus erythematosus (SLE), polymyositis ...
Ciang, NCO, Isenberg, DA, Pereira, N
core
Vogt-Koyanagi-Harada Syndrome in Two Patients with Immunoglobulin A Nephropathy [PDF]
We describe herein 2 patients who developed Vogt-Koyanagi-Harada syndrome in the course of renal biopsy-proven immunoglobulin A (IgA) nephropathy. A 61-year-old man with an 11-year history of IgA nephropathy and a 16-year history of thyroiditis, and a 56-
Masuda, Ikuya +5 more
core +1 more source
Prognostic impact of coronary microcirculation abnormalities in systemic sclerosis: a prospective study to evaluate the role of non-invasive tests [PDF]
INTRODUCTION: Microcirculation dysfunction is a typical feature of systemic sclerosis (SSc) and represents the earliest abnormality of primary myocardial involvement.
CAULI, ALBERTO +9 more
core +1 more source

