Results 11 to 20 of about 3,371 (182)

Scleroderma renal crisis: Case reports and update on critical issues [PDF]

European Journal of Rheumatology, 2021
To date, scleroderma renal crisis (SRC) remains a life-threatening complication in patients affected by systemic sclerosis (SSc), with high morbidity and mortality.
Elisabetta Zanatta, Veronica Codullo, Yannick Allanore   +2 more
doaj   +3 more sources

Complement activation in atypical hemolytic uremic syndrome and scleroderma renal crisis: a critical analysis of pathophysiology

Brazilian Journal of Nephrology, 2018
Scleroderma is an autoimmune disease that affects multiple systems. While pathophysiologic mechanisms governing the development of scleroderma are relatively poorly understood, advances in our understanding of the complement system are clarifying the ...
Roman Zuckerman, Arif Asif, Eric J. Costanzo, Tushar Vachharajani   +3 more
doaj   +5 more sources

Scleroderma renal crisis with coexisting segmental arterial mediolysis presenting as intraperitoneal bleeding: a case report

Journal of Medical Case Reports, 2019
Background Segmental arterial mediolysis is a rare nonarteriosclerotic and noninflammatory vascular disease that may cause intraperitoneal bleeding. Scleroderma renal crisis is a rare complication of systemic sclerosis, leading to severe hypertension and
Shohei Kaneko, Eri Watanabe, Mai Abe, Shinji Watanabe, Hiroki Yabe, Shigehiro Kojima, Kenji Takagi, Keiji Hirai, Yoshiyuki Morishita, Chihiro Terai   +9 more
doaj   +2 more sources

Hyponatremia in a patient with scleroderma renal crisis: a potential role of activated renin-angiotensin system

BMC Nephrology, 2012
Background Scleroderma renal crisis is an important complication of scleroderma (systemic sclerosis) that is associated with significant morbidity and mortality.
Fukasawa Hirotaka, Furuya Ryuichi, Ishigaki Sayaka, Kinoshita Naoko, Isobe Shinsuke, Fujigaki Yoshihide   +5 more
doaj   +2 more sources

Favourable Outcome of Scleroderma Renal Crisis [PDF]

Journal of the Royal Society of Medicine, 1996
Severe hypertension and rapidly progressive acute renal failure is a well recognized complication of scleroderma, often referred to as the renal crisis, and widely thought to cause irreversible deterioration in renal function. With the advent of angiotensin-converting-enzyme inhibitors (ACE-I) the outlook for patients with this condition has ...
D A, Collins, S, Patel, J B, Eastwood, B E, Bourke   +3 more
openaire   +3 more sources

Scleroderma with crescentic glomerulonephritis: a case report

Journal of Medical Case Reports, 2008
Introduction Systemic sclerosis or scleroderma is an autoimmune rheumatic disease characterized by organ-based fibrosis. Renal involvement in scleroderma occurs mainly in the form of scleroderma renal crisis, affecting 5 to 10% of patients.
Ramaswami Arunachalam, Kandaswamy Thiraviam, Rajendran Tholappan, Jeyakrishnan Kizhake, Aung Hla, Iqbal Mohammaed, Jacob Chakko K, Zinna Haji, Kafeel Gazala   +8 more
doaj   +2 more sources

Crise renal como manifestação inicial de esclerose sistêmica sine scleroderma Renal crisis as the initial clinical manifestation in systemic sclerosis sine scleroderma

Revista Brasileira de Reumatologia, 2004
A esclerose sistêmica (ES) sine scleroderma é uma doença rara, caracterizada pelo acometimento visceral (geralmente gastrintestinal, pulmonar ou vascular periférico) da ES, na ausência da característica fibrose cutânea.
Simone Appenzeller, Percival D. Sampaio-Barros, Adil M. Samara, João Francisco Marques Neto   +3 more
doaj   +2 more sources

Scleroderma Renal Crisis: A Pathology Perspective [PDF]

International Journal of Rheumatology, 2010
Scleroderma renal crisis (SRC) is an infrequent but serious complication of systemic sclerosis (SSc). It is associated with increased vascular permeability, activation of coagulation cascade, and renin secretion, which may lead to the acute renal failure typically associated with accelerated hypertension.
Batal, Ibrahim, Domsic, Robyn T., Medsger, Thomas A., Bastacky, Sheldon   +3 more
openaire   +3 more sources

Scleroderma Renal Crisis in Mixed Connective Tissue Disease With Full Renal Recovery Within 3 Months: A Case Report With Expanding Treatment Modalities to Treat Each Clinical Sign as an Independent Entity

Journal of Investigative Medicine High Impact Case Reports, 2017
Mixed connective tissue disease (MCTD) is a rheumatologic overlap syndrome that can present with symptoms of systemic lupus erythematous, scleroderma, and polymyositis.
Jordana Cheta MD, Suresh Rijhwani MD, Harlan Rust MD   +2 more
doaj   +3 more sources

Scleroderma Renal Crisis in a Normotensive Patient [PDF]

Kidney International Reports, 2016
INTRODUCTION S ystemic sclerosis (scleroderma) is an autoimmune disorder of unclear etiology that leads to fibrosis and vascular injury of the skin and multiple organs, including the lungs, heart, gastrointestinal tract, kidneys, and the musculoskeletal system.
Efua Asamoah-Odei
doaj   +3 more sources